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Completed

NCT Number: NCT04204746

The Affecting Factors on Airway Temperature and Moisture

There is no literature information about the flow rate of fresh gas mixture (air+O2) in the patients who underwent general anesthesia. Different flow rates of fresh gas mixture are used in both the investigator's hospital and the experiences of the anesthesiologists. It is aimed to study the effects of different fresh gas flow rates on the rate of temperature and moisture of the airway of patients who underwent general anesthesia.

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Key information

Conditions

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

About this study

Under physiological conditions, inhaled air is heated and humidified as it passes through the nose and upper airways until reaching the alveoli. This mechanism is bypassed by endotracheal intubation. Ventilation with dry and cold compressed gases leads to loss of water and heat from the respiratory tract. Drying of the respiratory tract can lead to destruction of the cilia and mucous membranes, resulting in decreased mucociliary transport and increased concentration of secretions.There is no definitive literature on fresh gas mix (oxygen + air) flow rates in patients under general anesthesia. This study aimed to investigate whether two fresh gas flow rates routinely employed in the authors' practice affected airway temperature and humidity.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients aged 18-65 years underwent general anesthesia -

Exclusion criteria

admitted to emergency and trauma, history of advanced cardiac disease, cigarette use ≥ 3 packet/day, pulmonary parenchymal disease such as malignancy or chronic obstructive pulmonary disease (COPD), history of thyroid disease, body mass index (BMI) greater than 30 kg/m2, alcohol and substance addiction, mentally deficiency, pregnancy or postpartum, fever and infection, drug use such that would influence thermoregulation such as vasodilators, hemorrhage > 5 mL/kg, and patients who declined to participate.

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Treatment and study plan

We will observe and evaluate the temperature and moisture in the respiratory circuit by a thermo-hygrometer.

Other

Primary outcomes

  1. Affect of two fresh gas flow rates (3lt/ 6lt min) on patients' airway temperature and humidity.

    Time frame: 2016-2018

    We will evaluate if different fresh gas flows effect on patients' airway temperature and moisture. We will evaluate by using a thermo-hygrometer fixed on anesthesia circuit.

Secondary outcomes

  1. Affect of different anesthetic gases (sevoflurane, desflurane) and drugs (propofol)on patients' airway temperature and humidity.

    Time frame: 2016-2018

    We will evaluate if different anesthetic gases (sevoflurane, desflurane) and drugs (propofol) effect on patients' airway temperature and moisture. We will evaluate by using a thermo-hygrometer fixed on anesthesia circuit.

Sponsors and collaborators

Lead sponsor

Selcuk University

Other

Registry information

Official study title

The Effects of Different Fresh Gas Flows and Different Anesthetics on Airway Temperature and Moisture in Patients Who Underwent General Anesthesia

Important dates

Study start
2016
Primary completion
2018
Study completion
2018
First posted
Dec 19, 2019
Registry last updated
Dec 20, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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