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OpenTrials
Completed

NCT Number: NCT06330649

The Acute Effect of and Energy Drink vs. Water Consumption on MAP, HR, and Energy Metabolism

The objective of this protocol is to investigate the effect of consumption of a commercially available energy drink beverage on blood pressure, heart rate, and energy metabolism

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Key information

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UT Arlington - Science and Engineering Innovation and Research Building

Arlington, Texas, 76019, United States

About this study

Energy drink consumption has gained a lot in popularity and represents one of the most rapidly growing segments of the beverage industry. While regularly discussed in media outlets etc. the cardiovascular effects are not well described or well known. For example, the impacts on various cardiovascular parameters range from improved, decreased, to not impacted at all depending on the source. This can be due to a number of reasons including, study protocol design, study population tested, energy drink product used, volume consumed, etc. Accordingly, this study aims to investigate the impact of acute consumption of a standard commercially available can of energy drink beverage on the following parameters.

  • Arterial blood pressure
  • Heart rate
  • Energy metabolism (oxygen consumption and carbon dioxide production

It is hypothesized that consumption of a 12 oz energy drink will result in modest elevations in arterial blood pressure, heart rate, and energy metabolism relative to when consuming of an equal volume of water.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Between ages 18-30
  • Must be free of reported cardiovascular, respiratory, and metabolic diseases.
  • Must be caffeine naïve
  • Must be fasted

Exclusion criteria

  • Food allergies
  • pregnant women
  • Breast feeding women
  • Individuals with cardiac, cardiovascular, respiratory, metabolic, and/or neurological disorders
  • taking any prescription vasoactive medications
  • allergies to spandex/lycra

Treatment and study plan

Energy Drink

Dietary Supplement

This is a commercially available energy drink

Water Control

Other

This is a commercially available bottled water

Primary outcomes

  1. Peripheral blood pressure in millimeters of mercury

    Time frame: baseline & 30, 60, 90, 120 min following beverage consumption

    blood pressure will be measured on the upper arm using standard procedures that are done in a doctors office.

  2. Oxygen consumption milliliters per kilogram of body weight per minute

    Time frame: baseline & 30, 60, 90, 120 min following beverage consumption

    This will be assessed using a metabolic cart to measure the amount of oxygen that is consumed by the body.

  3. Heart rate in beats per minute

    Time frame: baseline & 30, 60, 90, 120 min following beverage consumption

    Heart will be measured using an electrocardiogram procedures that are done in a doctors office.

Sponsors and collaborators

Lead sponsor

The University of Texas at Arlington

Other

Registry information

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Mar 26, 2024
Registry last updated
Apr 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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