Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males

The study is designed to identify and validate new protein biomarkers in blood related to testosterone activity. Thirty healthy young males underwent pharmaceutical castration to lower testosterone levels. After three weeks the subjects received an intramuscular injection of testosterone undecanoate. Blood samples from just before pharmaceutical castration, three weeks after castration, and one week after injection of testosterone undecanoate were collected representing normal testosterone levels, low testosterone levels, and testosterone at eugonadal levels.

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Key information

Conditions

Hypogonadism, Male Endocrine System Diseases Eunuchism Gonadal Disorders Hypogonadism

Age range

20 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

healthy males

Exclusion criteria

use of anabolic steroids, use of narcotics,

Treatment and study plan

GnRh antagonist

Drug

Primary outcomes

Protein biomarkers

Time frame: 48 months

Finding new protein biomarkers related to testosterone response

Sponsors and collaborators

Lead sponsor

Lund University

Other

Registry information

Official study title

Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males Before and After Pharmacological Castration

Important dates

Study start: 2015
Primary completion: 2015
Study completion: 2015
First posted: May 30, 2018
Registry last updated: May 30, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed