Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06469788

Testimonials and Navigation in Rheumatology

The overall goal of this study is to determine whether a novel, multi-modal, patient-directed behavioral intervention initiated in rheumatology clinics is an effective approach to improve uptake of updated COVID-19 vaccine.

Recruiting

Interested in participating?

Request Info

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Alabama at Birmingham, Birmingham, Alabama, United States

Loading trial locations.

About this study

Black and Latinx persons are at higher risk for certain autoimmune and inflammatory rheumatic diseases (AIRD) and have experienced worse COVID-19 outcomes compared to their white counterparts. Given the risks of severe COVID-19 outcomes such as hospitalization and death in people with AIRD, COVID-19 vaccine is recommended in this population. Historically, overall vaccine uptake among people with AIRDs has been low, and this vaccine reluctance has extended to COVID-19 vaccination. While additional COVID-19 vaccine doses have offered considerable added protection against severe outcomes, only 20% of all vaccinated persons in Alabama (AL) and 45% in Massachusetts have obtained an additional dose of COVID-19 vaccine as of October 2022. Racial and ethnic minority groups have faced disparities in obtaining subsequent COVID-19 vaccines, particularly in under-resourced communities, including those in Alabama and Massachusetts. Together, these obstacles exacerbate existing health inequities among people of color and perpetuate worse COVID-19 outcomes.

We will conduct a randomized controlled study to test an intervention that seeks to address gaps in COVID-19 vaccine information and access inequities common in Black and Latinx populations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults (18+ years) with known AIRD
  • Black race and/or Latinx ethnicity
  • Individuals who have not obtained the updated COVID-19 vaccine series (self-report)

Exclusion criteria

-Lack of access to phone

Treatment and study plan

Video comprised of AIRD patient narratives on COVID-19 vaccination thoughts and experiences

Behavioral

Participants will watch video focused on the importance of receipt of updated COVID-19 vaccination in patients with AIRD

Video on the importance of good oral health for patients with AIRD

Behavioral

Participants will watch video on the importance of good oral health in AIRD patients.

Other names: Attention Control

Brochure on COVID-19 vaccination in AIRD patients

Behavioral

Participants

Patient Navigation

Behavioral

Participants will receive phone calls from patient navigators to provide support and information for receipt of updated COVID-19 vaccination in patients with AIRD

Brochure on the importance of good oral health in AIRD patients

Behavioral

Participants will receive a brochure on the importance of good oral health in AIRD patients.

Primary outcomes

  1. Receipt of updated COVID-19 vaccination.

    Time frame: 3 months

    We will measure rates of receipt of updated COVID-19 vaccination.

Study contacts

Contact information is provided by the study sponsor or research team.

Mary A Wilkenson, Clinical Research Coordinator, BS

CONTACT

[email protected]

205-996-7875

Paolo Rusconi, Project Director, PhD

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

University of Alabama at Birmingham

Other

Collaborators

  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
  • National Institute on Minority Health and Health Disparities (NIMHD)

Registry information

Official study title

Improving COVID-19 Vaccine Uptake Among Racial and Ethnic Minority Groups With Rheumatic Diseases

Acronym: TANGO

Important dates

Study start
2024
Primary completion
2027
Study completion
2028
First posted
Jun 24, 2024
Registry last updated
May 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.