Ten-year Outcomes After AF Ablation

Ablation of atrial fibrillation (AF) using pulmonary vein isolation is employed when patients do not respond favorably to medical therapy. Successful procedures are accomplished in the majority of patients, but the outcome after many years of follow-up after ablation is unknown.

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Key information

Conditions

Atrial Fibrillation Arrhythmias, Cardiac Cardiovascular Diseases Heart Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Valley Hospital

Ridgewood, New Jersey, 07450, United States

About this study

A prospectively identified cohort of 445 patients who demonstrated freedom from AF for at least one year following ablation (single procedure in 391, 87.9%) was followed for 66.0 ± 34.0 months. Patients were seen at least annually as outpatients, and underwent regular ECG monitoring, especially if there were symptoms suggestive of recurrent arrhythmia. Continued absence of arrhythmia was defined as freedom from AF or flutter > 30 secs.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Prior AF ablation procedure
No AF for one year post ablation

Exclusion criteria

Geographic inaccessibility
Longstanding persistent AF
Recurrent AF within one year of ablation
Prior AF ablation

Treatment and study plan

Primary outcomes

Atrial fibrillation or flutter > 30 secs

Time frame: More than one year after successful primary ablation or redo procedure within 6 mos

Sponsors and collaborators

Lead sponsor

Valley Health System

Other

Registry information

Official study title

Long-term Outcome After Initially Successful Catheter Ablation of Atrial Fibrillation by Pulmonary Vein Isolation: a Ten-Year Cohort Study

Important dates

Study start: 2002
Primary completion: 2012
Study completion: 2012
First posted: Jun 3, 2013
Registry last updated: Dec 16, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed