NCT Number: NCT07107386
The TIME Study is a research project aiming to understand the body's natural rhythms. The goal is to see how daily and weekly changes in our bodies-from what's happening at a molecular level to data from wearable devices-are connected.
What is the study about? This study is trying to create a detailed map of how a person's body changes over time. By looking at information from blood, urine, and other samples, as well as data from smartwatches and other devices, researchers want to learn how our bodies' natural cycles work in healthy older adults. The long-term goal is to use this knowledge to help develop more personalized healthcare in the future.
Who can participate? The study is looking for healthy adults, age 55 or older, who have a smartphone and are able to travel to the Buck Institute in Novato, California, for study visits.
Participants will be asked to:
Attend weekly visits over 11 weeks to provide blood and other samples.
Wear health-tracking devices like a smart ring and watch.
Use a smartphone app to answer questions about their daily routines.
Complete two "challenge" tests, including drinking a glucose solution and exercising on a stationary bicycle.
Return for follow-up visits after 6 and 12 months.
Are there any risks or benefits? Benefits: There are no direct health benefits for participants. However, the information gained will help scientists create better diagnostic tools and treatments for future generations.
Risks: The main risks are minor discomfort from things like blood draws or skin irritation from the wearable devices. All personal information and data are kept private and secure.
Interested in participating?
Request Info55 year and older
All sexes
Observational
Novato, California, 94945, United States
Location status: Recruiting
Alison Le, Project Manager
CONTACT
Brianna Stubbs, Research Assistant Professor, PhD.
PRINCIPAL_INVESTIGATOR
Brianna Stubbs, Research Assistant Profressor, PhD.
CONTACT
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 12 months
Establish a publicly shareable reference dataset integrating blood-based proteomic, metabolomic, and lipidomic profiles with continuous digital health data and microbiome samples from healthy older adults over time, capturing daily, weekly, and perturbation-induced physiological dynamics.
Time frame: 12 months
Identify and quantify temporal correlations between blood-derived molecular biomarkers and physiological signals collected via wearable devices, including responses to standardized challenges.
Contact information is provided by the study sponsor or research team.
Alison Le, Project Manager
CONTACT
Brianna Stubbs, Research Assistant Professor, PhD.
CONTACT
Buck Institute for Research on Aging
Other
An Observational, Longitudinal Study to Characterize the Dynamic Structure of Molecular and Digital Health Data in Healthy Older Adults
Acronym: TIME
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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