University of Florida College of Dentistry Dental Clinical Research Unit
Gainesville, Florida, 32610, United States
Location status: Recruiting
Location contact
Dayane Oliveira, DDS, MS, PhD
PRINCIPAL_INVESTIGATOR
Renita Jenkins, CCRC, CDA
CONTACT
NCT Number: NCT06418958
Red light has been shown to be less harmful than blue light in vitro and in vivo. Although red light has been already introduced in the market and is currently being used in patients for several reasons, no data exist on the use of red light applied to restorative procedures. This study aims to specifically measure the in vivo temperature rise in simulated restorative procedures using blue light (standard) and red light and its post-operative sensitivity rates.
Interested in participating?
Request Info21 year–35 year
All sexes
Interventional
Not applicable
Gainesville, Florida, 32610, United States
Location status: Recruiting
Dayane Oliveira, DDS, MS, PhD
PRINCIPAL_INVESTIGATOR
Renita Jenkins, CCRC, CDA
CONTACT
Light-cured materials revolutionized dentistry as they allowed to control the setting of the materials in a timely manner simply upon light exposure. Although blue light has been routinely used to cure dental restorative materials for over 50 years, there are still potential risks to dental patients. These risks include gingiva burn or recession and pulp inflammation that can lead to necrosis in more severe situations due to the heat generated by this short wavelength (blue light). In addition, blue light has direct deleterious effects on cells, including irreversible imbalance in reactive oxygen species (ROS), damage to the mitochondrial DNA, and promoting collagen degradation. On the other hand, long wavelengths (such as red light) are known to have opposite effects, reducing inflammation and increasing cell proliferation. Although red light has been already introduced in the market and is currently being used in patients for several reasons, no in vivo data exist on the use of red-light applied to restorative procedures. Thus, this study aims to specifically measure the in vivo temperature rise in the tooth and gingival tissues surrounding restorative procedures using blue light (standard of care) and red light (investigational device) and evaluate/compare its post-operative sensitivity rates. The research hypothesis is that red light will generate less heat and less post-operative sensitivity than blue light (standard of care) while being used in dental restorative procedures.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Light Curing with Red Light
Light Curing with Blue Light
Time frame: During restorative procedure.
Temperature changes in degrees Celsius will be live-recorded by means of temperature probes for surface temperature acquisition.
Time frame: One week (±2 days) after intervention.
All patients will be called after the restoration(s) were placed to follow-up on any possible post-operative sensitivity or other questions or concerns. Post-operative sensitivity will be recorded as present or absent. If present, the post-operative sensitivity will be classified as mild, moderate, or severe according to the visual analog scale (VAS).
University of Florida
Other
In Vivo Temperature Changes Caused by Exposure to Short- and Long-wavelengths
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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