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NCT Number: NCT07725003

Telerehabilitation Based Motor Relearning Program and Telerehabilitation Based Conventional Physical Therapy in Stroke

This study aims to compare the effects of telerehabilitation based motor relearning program and telerehabilitation based conventional physical therapy on motor function and balance in stroke patients.

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Key information

Age range

40 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Several recent studies have demonstrated the effectiveness of telerehabilitation in stroke rehabilitation. An umbrella review published in 2024 evaluated systematic reviews and meta-analyses conducted between 2010 and 2023 and concluded that telerehabilitation is effective in enhancing mobility, upper limb function, and balance in post-stroke patients. The review also emphasized the technology's role in increasing access to rehabilitation services and reducing treatment delays, especially in rural or underserved areas. The findings support the integration of telerehabilitation into standard stroke care practices.

A randomized controlled trial conducted in 2023 on 60 post-stroke patients compared home-based telerehabilitation with traditional outpatient therapy over an 8-week period. Participants in both groups demonstrated significant improvements in the Berg Balance Scale (BBS) and Fugl-Meyer Assessment (FMA) scores. However, the telerehabilitation group reported slightly higher patient satisfaction and adherence, indicating that home-based telerehabilitation is a feasible and effective alternative for improving motor function and balance in stroke survivors.

A longitudinal observational study published in 2022 involving 120 individuals in the subacute and chronic phases of stroke recovery explored balance recovery mechanisms. The findings showed that balance impairments are most responsive to intervention within the first six months after stroke, corresponding with a heightened period of neuroplasticity. The study highlighted the importance of early, structured, and task-specific rehabilitation during this critical phase, supporting the potential application of the Motor Relearning Program (MRP).

A pilot study published in 2021 evaluated the feasibility of delivering task-specific therapy through telerehabilitation using video conferencing. The intervention included functional training exercises for 25 stroke patients aged 45-70 years over six weeks. Significant improvements were observed in trunk control, sit-to-stand transfers, and walking ability, with positive participant feedback and no reported adverse events. The findings suggest that telerehabilitation can effectively deliver neurophysiological principles such as motor learning.

A clinical trial conducted in 2020 involving 40 subacute stroke patients assessed the effectiveness of task-specific training based on the Motor Relearning Program (MRP). Participants performed repetitive, goal-oriented functional tasks, including transfers and walking. After four weeks, the intervention group demonstrated significant improvements in trunk control and balance compared with the group receiving standard physiotherapy, indicating that MRP is highly effective in improving motor control and coordination when delivered in person.

A systematic review published in 2020 examined 22 randomized trials investigating telerehabilitation interventions for stroke recovery. The findings indicated that telerehabilitation was non-inferior to conventional in-clinic therapy in improving gait, balance, and upper limb function. The review further emphasized that structured and patient-specific telerehabilitation is particularly beneficial during the subacute stage when recovery potential is highest.

A controlled trial published in 2017 assessed the effectiveness of telerehabilitation in improving motor function after stroke. Fifty stroke patients aged 40-70 years were randomly assigned to either a telerehabilitation group or a conventional therapy group. After eight weeks, both groups showed significant improvements in motor function, while the telerehabilitation group achieved superior balance outcomes, demonstrating the effectiveness of remotely delivered motor-focused interventions.

A foundational publication in 2015 described the theoretical framework of the Motor Relearning Program (MRP). The program emphasizes active participation, task analysis, and repetitive practice to retrain functional movements. Based on principles of motor control and neuroplasticity, MRP is considered particularly effective for post-stroke patients during the recovery period of 3-12 months. Although widely accepted for face-to-face rehabilitation, its application through digital platforms remains underexplored.

Another meta-analysis published in 2015 evaluated telerehabilitation programs for stroke patients and concluded that while telerehabilitation improves overall function, many interventions lacked specificity and did not incorporate evidence-based motor learning principles. The findings highlighted the need to strengthen telerehabilitation frameworks through structured approaches such as the Motor Relearning Program.

Despite the increasing adoption of telerehabilitation in post-stroke care, notable gaps remain in the current body of research. No study to date has directly compared conventional telerehabilitation programs, which are typically based on general physiotherapy principles, with telerehabilitation approaches specifically structured around the Motor Relearning Program. While existing evidence supports the use of general telerehabilitation in improving motor function, balance, and participation among stroke survivors, these programs often lack the task-specific, neuroplasticity-driven framework that defines the Motor Relearning Program. Separately, MRP-based interventions delivered in clinical settings have demonstrated superior outcomes in balance, functional mobility, and motor recovery compared to routine therapy. However, a head-to-head comparison between conventional telerehabilitation and MRP-based telerehabilitation has not yet been explored in published literature. Furthermore, most existing studies are limited by small, homogenous sample sizes, non-standardized outcome measures, and the absence of long-term follow-up. The integration of advanced technologies such as wearable sensors and real-time feedback into telerehabilitation protocols also remains underdeveloped. These gaps highlight the urgent need for rigorous, comparative, and technology-integrated research to evaluate the effectiveness of structured, MRP-based telerehabilitation in diverse stroke populations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

* Adults aged 40-70 years.

  • Male or female participants.
  • Diagnosed with ischemic or hemorrhagic stroke 3-12 months prior to enrollment.
  • Medically stable and cleared to participate in physical rehabilitation.
  • Mini-Mental State Examination (MMSE) score ≥24.
  • Able to understand and follow verbal instructions.
  • Have access to a smartphone, tablet, or computer with a stable internet connection for telerehabilitation sessions.
  • Willing and able to provide written informed consent.

Exclusion criteria

* MMSE score <24 or severe cognitive impairment.

  • Presence of other neurological disorders (e.g., Parkinson's disease or multiple sclerosis).
  • Uncontrolled hypertension or recent cardiac event.
  • Severe visual, auditory, or communication impairments that prevent participation.
  • Currently enrolled in another structured rehabilitation program.
  • Any musculoskeletal or medical condition that would interfere with safe participation in the intervention.

Treatment and study plan

Telerehabilitation Based Motor Relearning Program

Other

Participants will receive a Motor Relearning Program (MRP) delivered through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, task-specific functional training, and cool-down. Exercises include sitting and standing balance training, trunk control, sit-to-stand practice, upper limb reaching, trunk rotation, weight-shifting, step training, walking practice, stair simulation, obstacle negotiation, dual-task activities, community mobility simulation, and functional transfer training. Exercise intensity will be moderate and progressively increased according to the participant's tolerance and functional performance.

Other names: MRP, Tas-Specific Motor Relearning, Telerehabilitation MRP

Conventional physical therapy

Other

Participants will receive conventional physiotherapy through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, exercise session, and cool-down. The program consists of active-assisted and active range-of-motion exercises, stretching, breathing exercises, strengthening exercises, weight-shifting activities, marching in place, gait training, dynamic mobility exercises, and light resistance exercises using Theraband where appropriate. Exercise intensity will be moderate and adjusted according to each participant's tolerance and clinical progress.

Other names: Standard physical therapy

Primary outcomes

  1. Fugl-Meyer Assessment (FMA) Motor Function Score

    Time frame: Baseline and after 6 weeks of intervention

    Change in motor function will be assessed using the Fugl-Meyer Assessment (FMA). The FMA evaluates motor recovery of the upper and lower extremities, with higher scores indicating better motor function.

  2. Berg Balance Scale (BBS) Score

    Time frame: Baseline and after 6 weeks of intervention

    Balance performance will be assessed using the Berg Balance Scale (BBS). The scale consists of 14 functional balance tasks, with higher scores indicating better balance.

Secondary outcomes

  1. Timed Up and Go (TUG) Test

    Time frame: Baseline and after 6 weeks of intervention

    Functional mobility will be assessed using the Timed Up and Go (TUG) Test by measuring the time required for a participant to stand up from a chair, walk 3 meters, turn, return, and sit down. Lower completion times indicate better functional mobility.

Study contacts

Contact information is provided by the study sponsor or research team.

Imran Amjad, phd

CONTACT

[email protected]

+923324390125

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Comparative Effects of Telerehabilitation Based Motor Relearning Program and Telerehabilitation Based Conventional Physical Therapy on Motor Function and Balance in Stroke Patients.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 24, 2026
Registry last updated
Jul 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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