Faculty of Medicine Siriraj Hospital, Mahidol University
Bangkok Noi, Bangkok, 10700, Thailand
NCT Number: NCT07546474
Out-of-hospital cardiac arrest (OHCA) is a life-threatening emergency where early cardiopulmonary resuscitation (CPR) by bystanders can significantly improve survival. Emergency dispatchers often guide bystanders to perform CPR over the phone, a method known as dispatcher-assisted CPR (DA-CPR). While this approach has increased bystander CPR rates worldwide, it relies on voice communication only, which may limit the dispatcher's ability to assess the situation and guide CPR effectively.
With advances in telecommunication technology, video-based communication has become more widely available. Telemedicine-assisted CPR (TA-CPR) allows dispatchers or emergency medical providers to see the patient and the rescuer through a live video call, potentially improving CPR performance by providing real-time visual feedback. However, evidence on whether this approach improves outcomes in real-world emergency medical service (EMS) systems is still limited.
This study aims to compare the effectiveness of TA-CPR with conventional DA-CPR in adult patients with suspected non-traumatic OHCA. The study is designed as a pragmatic cluster-randomized controlled trial conducted within a hospital-based EMS system in Bangkok, Thailand. Instead of randomizing individual patients, the CPR instruction protocol is assigned by month (cluster randomization). During each month, all eligible patients receive either the TA-CPR protocol or the DA-CPR protocol.
In both groups, CPR instructions are first provided through voice communication to avoid delaying the start of chest compressions. In the TA-CPR group, responders may switch to video communication if it is feasible, depending on factors such as the caller's device capability and the availability of another person to hold the camera. In the DA-CPR group, only voice communication is used throughout.
The study includes adult patients (aged 18 years or older) with suspected non-traumatic cardiac arrest who are managed by the participating EMS unit. Patients are excluded if resuscitation is declined, if the location is unsafe, if the cardiac arrest is witnessed by EMS personnel, or if communication barriers prevent CPR instructions.
The primary outcome of the study is the proportion of patients who receive bystander CPR before EMS arrival. Secondary outcomes include whether bystanders continue chest compressions until EMS arrives, how well responders follow the assigned protocol, and selected patient outcomes such as return of spontaneous circulation and survival.
Data are collected from an EMS cardiac arrest registry and hospital medical records. Audio recordings of dispatcher and responder communications are reviewed to assess adherence to the study protocols. The results of this study will help determine whether adding video communication to dispatcher-assisted CPR provides additional benefit in real-world EMS settings and inform future implementation of telemedicine in emergency care systems.
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Bangkok Noi, Bangkok, 10700, Thailand
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Participants receive dispatcher or EMS-guided cardiopulmonary resuscitation (CPR) with an initial audio-based instruction followed by real-time video communication when feasible. Video guidance is implemented based on device capability, connectivity, and availability of an additional bystander to assist with video transmission. If video is not feasible, CPR instructions continue via audio.
Participants receive conventional dispatcher-assisted CPR instructions delivered exclusively via audio (telephone communication) without the use of video support.
Time frame: From enrollment to the end of resuscitation at 1 day
Proportion of patients with suspected out-of-hospital cardiac arrest who receive cardiopulmonary resuscitation from a bystander prior to EMS arrival
Time frame: From enrollment to the end of resuscitation at 1 day
Proportion of patients receiving continuous chest compressions by bystanders at the time EMS arrives
Time frame: From enrollment to the audit protocol at 4 weeks
Proportion of cases in which EMS personnel adhere to all required steps of the assigned CPR instruction protocol (including successful video use in TA-CPR when applicable)
Time frame: From enrollment to the end of resuscitation at 1 day
Return of spontaneous circulation (ROSC) at emergency department
Time frame: During hospitalization (assessed up to 5 days)
Time frame: During hospitalization (assessed up to 24 weeks)
Siriraj Hospital
Other
Acronym: TACTIC
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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