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Completed

NCT Number: NCT07592559

tDCS and the Gaze Cueing Effect

This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.

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Key information

Conditions

tDCS Congruency Cues Type SOA

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

School of Foreign Languages, University of Electronic Science and Technology of China

Chengdu, Sichuan, 611731, China

About this study

This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.To examine the distinct functions of the OFC in processing social versus non-social stimuli, participants were randomly assigned to one of three tDCS groups: anodal, cathodal, or sham. Following stimulation, all participants completed a spatial cueing task involving both gaze and arrow cues. Two stimulus onset asynchrony (SOA) conditions (200 ms and 600 ms) were implemented to investigate how timing modulates the processing of these cues within the rOFC.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy subjects without past or current psychiatric or neurological disorders

Exclusion criteria

  • history of head injury
  • no implants in the head
  • medical or psychiatric illness.

Treatment and study plan

Gaze cues

Behavioral

use eye gaze images as cues

Arrow cues

Behavioral

use arrow images as cues

SOA 200 ms

Behavioral

The stimulus onset asynchrony (SOA) between the cue and the target was 200 ms.

SOA 600 ms

Behavioral

The stimulus onset asynchrony (SOA) between the cue and the target was 600 ms.

Congruent

Behavioral

The cue is spatially congruent with the target.

Incongruent

Behavioral

The cue is spatially incongruent with the target.

Primary outcomes

  1. Reaction time to the judgment of the target location.

    Time frame: 1 hour

    The primary analysis focused on the reaction times for judging the target location under each condition.

Secondary outcomes

  1. Magnitude of the cueing effect

    Time frame: 1 hour

    This index is derived by subtracting the congruent reaction time from the incongruent reaction time to quantify the magnitude of the cueing effect.

Sponsors and collaborators

Lead sponsor

University of Electronic Science and Technology of China

Other

Registry information

Official study title

Influence of Transcranial Direct Current Stimulation Applied to the Right Orbitofrontal Cortex on Gaze and Arrow Cueing Effects

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
May 18, 2026
Registry last updated
May 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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