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Completed

NCT Number: NCT02646956

Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults

The goal of the study is to determine whether there are age-, diet- and genetically-related differences in the perception of sweeteners, both nutritive and non-nutritive.

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Key information

Conditions

Development

Age range

7 year–60 year

Sex eligibility

All sexes

Study type

Observational

About this study

This is an observational 3-day study of children between the ages of 7 and 14 and their mothers. A variety of psychophysical methods determined liking for each of the sweeteners and saliva samples were obtained for genotyping of taste receptor genes. Anthropometric and dietary intake measures were also collected.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy

Exclusion criteria

  • Allergies and taking medication that affected taste

Treatment and study plan

sweeteners

Other

Participants tasted a variety of nutritive and nonnutritive sweeteners

Primary outcomes

  1. Liking for the taste of sweeteners measured via the 3-point facial hedonic scale.

    Time frame: Through study completion, an average of 6 months.

  2. Liking for the taste of sweeteners measured via the 5-point facial hedonic scale

    Time frame: Through study completion, an average of 6 months.

  3. Liking for the taste of sweeteners measured via the Monell forced-choice, paired-comparison tracking procedure.

    Time frame: Through study completion, an average of 6 months.

Secondary outcomes

  1. Genotyping of taste receptor genes via saliva donation

    Time frame: Through study completion, an average of 6 months

    Genotyping will be completed to measure associations between individual taste receptor genotypes and liking of sweeteners.

  2. BMI calculated from body weight and height measures

    Time frame: Through study completion, an average of 6 months

    BMI will be calculated to examine associations between this measure and liking for sweeteners.

  3. One day dietary intake collected via the Automated Self-Administered 24-hour dietary recall (ASA24).

    Time frame: Through study completion, an average of 6 months

    Dietary recall will be completed to examine associations between added sugar intake and liking for sweeteners.

Sponsors and collaborators

Lead sponsor

Monell Chemical Senses Center

Other

Registry information

Acronym: TNNS

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Jan 6, 2016
Registry last updated
Jan 6, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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