CHU de Nice
Nice, 06003, France
Completed
NCT Number: NCT04899011
Taste Disturbance After Middle Ear Surgery: Frequency, Duration, Influence of Chorda Tympani Injury and Quality of Life
Chorda tympani nerve (CTN), is a branch of nerve VII, and has two componants: taste sensation from the anterior two thirds of the tongue and salivary secretion from submandibular and sublingual salivary glands.
CTN go throw middle ear between malleus and incus. Due to it anatomic localization, CTN is frequently damage during otologic surgery.
Taste disturbance after middle ear surgery has been describe in literature but results of the various studies are very heterogenous. Moreover, there is no consensus to preserved or sacrificed a traumatize CTN.
We will use questionnaire to evaluate frequency, duration and characteristics of taste disturbance after ear surgery and the impact on the quality of life for those with symptoms.
We will evaluate the Influence of type of CTN injury on taste disturbance.
Completed
Looking for future studies?
Notify MeKey information
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Patient undergoing middle ear surgery
- Acceptation to participate
- under 18 years old, parental authorization.
Exclusion criteria
- Taste disturbance before surgery
- Patients with guardianship or tutelage measure
Treatment and study plan
Questionnaire
OtherQuestionnaire about taste and salivary disturbance before surgery, 10 days, 4 months and 1 year after surgery.
Questionnaires include characteristics of taste disturbance, and specific impact on quality of life.
Primary outcomes
-
Frequency, duration and characteristics of taste and salivary disturbance after middle ear surgery and impact on quality of life.
Time frame: 1 year
Taste and salivary disturbance will be measure with questionnaire before and during 1 year after middle ear surgery
Secondary outcomes
-
Influence of CTN injury type: stretch versus sectionned, influence of otologic desease
Time frame: 1 day
Measure with surgeon questionnaire
-
Influence of use between endoscope or microscope surgery
Time frame: 1 day
Measure with surgeon questionnaire
Sponsors and collaborators
Lead sponsor
Centre Hospitalier Universitaire de Nice
Other
Registry information
Important dates
- Study start
- 2021
- Primary completion
- 2023
- Study completion
- 2023
- First posted
- May 24, 2021
- Registry last updated
- Mar 10, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.