Targeted Melanoma Detection With Skin Self-Examination During COVID-19 Restricted Physician Access

The proposed work will assess the effectiveness of targeted melanoma detection (TMD) with SSE education delivered remotely to women who had a screening mammogram. The effect of TMD with SSE education will be assessed with a randomized control trial among women served by Northwestern Medicine in rural, suburban and metropolitan communities. Women who identify concerning moles will choose among three options: a) watch the mole to see if the border, color or diameter of the mole changes b) send a picture of the mole to the PI for consideration of mole self-sampling, or c) make an appointment with my healthcare provider to check the mole. As required a physician will supervise women, who will perform non-invasive mole self-sampling with non-invasive adhesive patches for genomic analysis of the concerning pigmented lesion (mole). If the genomic analysis suggests that the concerning mole may be a melanoma, then the recommendation will be to have the mole biopsied.The effectiveness of acquired samples suggestive of melanoma will be examined by the obtaining the pathology reports of biopsied moles. Health care providers' (HCPs) clinical/pathologic assessment of concerning moles will be identified in the Northwestern Medicine electronic health record (EHR) system.

Inclusion criteria

• Adult women (aged 18 and older) with no upper age limit, who had a screening mammogram from January 1, 2019 to February 28, 2020.
• Able to read English
• Vision enough to read a newspaper
• Self-perception of their potential melanoma risk
• Willing to perform SSE either alone or with a skin check partner
• Willing to complete monthly surveys for 3 months and receive monthly text messages to personal mobile phone
• Have home Internet access and phone with ability to take a picture of a mole
• Have access to Federal Express or US Postal Service Express Mail to send mole self-sampling kits
• Willing to allow the research team access to their electronic health record to abstract physician assessment of concerning moles, biopsy results and treatment
• Willing to provide up-to-date email address, mailing address and telephone number

Inclusion criteria

of skin check partner, who may be a man or a woman, to have mole self-sampled

• Male or female over the age of 18 years
• Able to read English
• Vision enough to read a newspaper

Exclusion criteria

• Male
• Female under the age of 18
• Unable to read English