Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients

The investigators will measure the pharmacokinetics of doripenem in skeletal muscle, subcutaneous adipose tissue, bronchoalveolar lavage and plasma of intubated intensive care patients.

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Key information

Conditions

Pneumonia Abdominal Infection Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Infections Intraabdominal Infections Lung Diseases Male Urogenital Diseases Respiratory Tract Diseases Respiratory Tract Infections Urinary Tract Infection Urinary Tract Infections Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Med. Univ. of Vienna

Vienna, 1090, Austria

About this study

Methods: microdialysis, blood sampling, bronchoalveolar lavage

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

endotracheal intubation; pneumonia or complicated abdominal infection or complicated urinary tract infection

Exclusion criteria

allergy to doripenem, hemodialysis

Sponsors and collaborators

Lead sponsor

Medical University of Vienna

Other

Registry information

Important dates

Study start: 2011
Primary completion: 2013
Study completion: 2013
First posted: Aug 11, 2011
Registry last updated: Aug 29, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed