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NCT Number: NCT07064200

TAP Block Timing Study

This study investigates whether administering TAP blocks pre-incision provides superior postoperative pain control and reduces opioid use along with other medications compared to post-incision administration in patients undergoing elective abdominal surgeries.

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Key information

Conditions

Bariatric or General Abdominal Surgeries Bariatric Surgery Patients

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Weill Cornell Medical College - NewYork-Presbyterian Hospital

New York, 10065, United States

Location status: Recruiting

Location contact

Cheguevara Afaneh, MD

PRINCIPAL_INVESTIGATOR

Hasan Ali

CONTACT

[email protected]

(646) 962-8462

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged between 18 and 65 years
  • Scheduled for elective bariatric surgery or other elective general abdominal surgeries
  • Proficient in English sufficient to understand study procedures and communicate effectively
  • Capable of providing informed consent

Exclusion criteria

  • Individuals under 18 years of age (minors)
  • Pregnant individuals
  • Prisoners
  • Individuals with cognitive impairments or otherwise unable to provide informed consent independently
  • Individuals with known allergies or contraindications to local anesthetics used in TAP blocks

Treatment and study plan

TAP Block

Other

the TAP block is a regional anesthesia technique that targets the somatic nerves supplying the anterior abdominal wall.

Primary outcomes

  1. Mean change in opioid consumption (MME) from index procedure to 90 days post-op

    Time frame: Up to 90 days post-operatively

    Opioid dosage quantities will be measured in morphine milligram equivalents (MME)

  2. Change in Pain Scores from index procedure on a numerical rating scale

    Time frame: 1, 3, 6, 24, 48, and 72 hours postoperatively

    Patient-reported pain on a scale of 1-10.

Secondary outcomes

  1. 1. Total Opioid Consumption in MME from Surgery to 90 Days Postoperatively

    Time frame: From end of surgery to 90 days post-op.

    Sum of all opioid use from surgery to 90 days, in MME

  2. Patient Satisfaction Score with Postoperative Pain Management at Discharge

    Time frame: At hospital discharge (within 3-5 days post-op)

    Satisfaction score using a 5-point Likert scale survey before discharge.

  3. Use of Non-Opioid Analgesics within 72 Hours

    Time frame: From end of surgery to 72 hours post-op

    Count of participants receiving non-opioid pain medications (e.g. acetaminophen, NSAIDs) within 72 hours post-op, including amount and type.

  4. Number of Participants with TAP Block-Related Adverse Events

    Time frame: From TAP block administration to 90 days post-op.

    Incidence of adverse events (e.g. local anesthetic toxicity, infection, bleeding) related to TAP block.

Study contacts

Contact information is provided by the study sponsor or research team.

Cheguevara Afaneh, MD

CONTACT

[email protected]

+1 646 962 8462

Hasan Ali

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Weill Medical College of Cornell University

Other

Registry information

Official study title

Transversus Abdominis Plane (TAP) Blocks in Bariatric and General Surgery: Does Timing Matter?

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Jul 14, 2025
Registry last updated
Jan 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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