Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07448558

Tailored Exercise to Reduce Aromatase Inhibitor Associated Musculoskeletal Symptoms

A randomized controlled study evaluating effect of tailored exercise compared to routine practice as a preventive measure of aromatase inhibitor associated musculoskeletal related symptoms in early breast cancer patients

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Patients With Early Breast Cancer Who Initiating Adjuvant Aromatase Inhibitor Behavior Breast Diseases Breast Neoplasms Motor Activity Neoplasms Neoplasms by Site Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine Siriraj Hospital, Mahidol University

Bangkok, 10700, Thailand

Location status: Recruiting

Location contact

Akarin Nimmannit, M.D

SUB_INVESTIGATOR

Concord Wongkraisri, M.D

SUB_INVESTIGATOR

Kanchana Inthiraj

SUB_INVESTIGATOR

Pisit Lertwanich, M.D

SUB_INVESTIGATOR

Suchaya Tanissa, M.D

SUB_INVESTIGATOR

Suebwong Chutapisit, M.D

SUB_INVESTIGATOR

Suthinee Ithimakin

CONTACT

[email protected]

0898127440

Suthinee Ithimakin, M.D

PRINCIPAL_INVESTIGATOR

CONTACT

[email protected]

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • breast cancer patients with starting adjuvant aromatase inhibitor within 4 weeks
  • able to read and write

Exclusion criteria

  • chronic arthritis
  • history of heart failure or acute coronary syndrome within 6 months
  • individuals who exercises regularly more than 150 minutes/week

Treatment and study plan

tailored exercise

Behavioral

tailored suitable exercise to individuals recommended for the aim of aerobic exercise at 150 minutes per week and strengthening exercise twice a week

Primary outcomes

  1. Aromatase inhibitor associated musculoskeletal symptoms (AIMSS)

    Time frame: 12 months

    occurrence of AIMSS

Secondary outcomes

  1. worsening pain

    Time frame: 12 months

    reduce numerical scale of pain more than 2 points

  2. body weight

    Time frame: 12 months

    body weight change

  3. quality of life FACT-ES

    Time frame: 12 months

    FACT-ES score

Study contacts

Contact information is provided by the study sponsor or research team.

Suthinee Ithimakin, M.D

CONTACT

[email protected]

+66898127440

Sponsors and collaborators

Lead sponsor

Mahidol University

Other

Registry information

Official study title

Effectiveness of Tailored Home-based Exercise on Aromatase Inhibitor-associated Musculoskeletal Symptoms in Breast Cancer Patients Receiving Adjuvant Aromatase Inhibitor: A Randomized, Controlled Trial

Acronym: TAILOR-Ex

Important dates

Study start
2026
Primary completion
2029
Study completion
2029
First posted
Mar 4, 2026
Registry last updated
Mar 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.