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Completed

NCT Number: NCT06374563

Tackling Pressure Ulcer Via Bee Venom Phonophoresis

This study aimed to investigate the efficiency of topical Bee Venom gel versus phonophoresis of Bee Venom gel to accelerate healing of chronic pressure ulcer

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Key information

Conditions

Bee Venom Phonophoresis Pressure Ulcer Pressure Ulcers Skin Diseases Skin Ulcer Skin and Connective Tissue Diseases

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Badr University in Cairo

Cairo, 11837, Egypt

About this study

In this study, the Bee Venom gel was prepared in a gel formula. Patients with chronic pressure ulcers were enrolled randomly into two different groups. Group 1 received a topical application of Bee Venom gel, 3 times per weeks. While group 2 received phonophoresis of Bee Venom gel using low frequency ultrasound, 3 times per week. The treatment lasted for 8 consecutive weeks. The Image J Software is used to measure the wound surface area before and after treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with stage II and III chronic neuropathic ulcers.

Exclusion criteria

  • Patients with chronic cardiac,
  • Patients with renal, and
  • Patients with hepatic diseases and
  • Diabetic patients. Additionally,
  • Patients with immunosuppressive diseases,
  • Patients with HIV, and
  • Anemia Patients

Treatment and study plan

group 1 received topical Bee venom gel

Other

Group 1 received a topical application of Bee Venom gel, 3 times per weeks. The wound dressing changed day after day and was cleaned every time with normal saline.

Group 2: Phonophoresis of Bee Venom gel

Other

group 2 received phonophoresis of Bee Venom gel using low frequency ultrasound, 3 times per weeks

Primary outcomes

  1. wound surface area wound surface area

    Time frame: Before starting treatment and after 8 weeks of treatment

    ImageJ Software was used to measure the wound size

  2. wound volume

    Time frame: Before starting treatment and after 8 weeks of treatment

    wound volume was measured through the volumetric measurement method using a syringe filled with saline

Sponsors and collaborators

Lead sponsor

Badr University

Other

Registry information

Official study title

Tackling Chronic Pressure Ulcer Via Bee Venom Phonophoresis

Acronym: ulcer

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Apr 18, 2024
Registry last updated
Apr 18, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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