Systems Biology of Amyotrophic Lateral Sclerosis (ALS)

The goal of this observational study is to identify molecular features in multiple clinical samples and/or the patient environment that are associated with ALS. Participants will collect biological samples and answer questionnaires regarding their health at each appointment with their ALS practitioner.

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Key information

Conditions

ALS ALS (Amyotrophic Lateral Sclerosis) Amyotrophic Lateral Sclerosis Central Nervous System Diseases Metabolic Diseases Motor Neuron Disease Nervous System Diseases Neurodegenerative Diseases Neuromuscular Diseases Nutritional and Metabolic Diseases Proteostasis Deficiencies Spinal Cord Diseases TDP-43 Proteinopathies

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patient of Dr. Espíndola at UFSC

Exclusion criteria

Treatment and study plan

Primary outcomes

Molecular features of biological samples that are predictive of ALS progression

Time frame: We will collect samples and health data from each participant from the time of diagnosis to their death or study termination, whichever comes sooner. Specific time frame: We will collect outcome measures through study completion, an average of 3 years.

Study contacts

Contact information is provided by the study sponsor or research team.

Momo Chief Science Officer, Head of Clinical Research, PhD

CONTACT

[email protected]

Raquel Clinical Research Coordinator, BS

CONTACT

[email protected]

425-368-5248

Sponsors and collaborators

Lead sponsor

Viome

Industry

Collaborators

Universidade Federal de Santa Catarina

Registry information

Important dates

Study start: 2025
Primary completion: 2030
Study completion: 2030
First posted: Jun 5, 2025
Registry last updated: Jun 5, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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