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Completed

NCT Number: NCT04680143

Systemic Erythropoietin Injection in Patients Having Optic Atrophy

The purpose of this treatment trial is to study the effect of systemic erythropoietin in patients having optic atrophy.

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Key information

Conditions

Optic Atrophy Cranial Nerve Diseases Eye Diseases Nervous System Diseases Optic Nerve Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

Alexandria Faculty of Medicine

Alexandria, Egypt

About this study

The purpose of this treatment trial is to study the effect of systemic erythropoietin in patients having optic atrophy. The intervention is systemic erythropoietin injections (eprax 10000 IU subcutaneous twice daily for three days).

Follow up after one month and three months by recording visual acuity and electro physiological studies.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Post papilledemic optic atrophy patients

Exclusion criteria

  • Refuse to give an informed consent

Treatment and study plan

Systemic erythropoietin injection

Drug

Systemic erythropoietin injections (eprax 10000 IU subcutaneous twice daily for three days).

Other names: Eprax 10000

Primary outcomes

  1. Visual acuity

    Time frame: 3 months

    VIsual acuity assessed at the follow up

  2. Pattern visual evoked Potential .

    Time frame: 3 months

    Pattern visual evoked Potential .in both eyes to use data of the normal fellow eye as patients' internal control

  3. Pattern electroretinogram

    Time frame: 3 months

    Pattern electroretinogram in both eyes to use data of the normal fellow eye as patients' internal control

Sponsors and collaborators

Lead sponsor

Alexandria University

Other

Registry information

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Dec 22, 2020
Registry last updated
Jul 13, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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