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Recruiting

NCT Number: NCT07468279

Synchronization of Theta to Influence Memory

This study aims to clarify relations between brain oscillations and two cognitive functions: cognitive control and memory.

Recruiting

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Key information

Age range

18 year–59 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Florida International University

Miami, Florida, 33199, United States

Location status: Recruiting

Location contact

George Buzzell

CONTACT

[email protected]

305-348-2868

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years and older
  • Fluent in English
  • Normal or corrected-to-normal vision
  • Willing to be photographed

Exclusion criteria

  • Must not have ever had an injury to the head that's caused you to be knocked out for a period of time (e.g., from a fall, blow to the head, road traffic accident).
  • Must not have an uncorrected vision or physical disability that interferes with your ability to see stimuli presented briefly on a computer screen or click a mouse button rapidly.
  • Must not have a history of epilepsy, convulsions, or seizures (except childhood febrile seizures).
  • Must not have a history of fainting or syncope.
  • For female participants, they must not be pregnant and/or must not think they might be pregnant.
  • Must not have skin problems like eczema, dermatitis, or open wounds on the scalp.
  • Must not have had prior brain surgery.
  • Must not have any metal located in the head/neck (except for dental fillings).
  • Must not have any devices or other implants located in/near their head. This includes cochlear implants and aneurysm clips, cardiac pacemaker, or any other implanted electronic device.
  • Must not have a current (active) alcohol or substance use disorder, must have no recent history of withdrawal symptoms, and must be able to safely abstain from alcohol and non-prescribed/illicit drugs for at least 24 hours before the session.
  • Must not have any alcohol on the day of the session, must limit alcohol consumption to no more than 2 drinks (if legally permitted) in the prior 24 hours, and must not use any non-prescribed or illicit drugs in the 24 hours before the session.
  • Must not be sick with a fever, sleep-deprived, or feel dizzy, unwell, or intoxicated.
  • Must also have eaten and had fluids but not have consumed more caffeine than they typically consume.
  • Must not be taking anticonvulsant/anti-epileptic drugs or have ever taken them within their lifetime.
  • Must not be taking benzodiazepines or have taken them within the past 3 months.
  • Must not have had a recent change (start, stop, dose change) for any psychiatric/psychotropic medications within the past 3 months.
  • Must not be taking Bupropion (Wellbutrin, Zyban), Tricyclic antidepressants (e.g., amitriptyline, imipramine, clomipramine, etc.), Antipsychotics (clozapine; chlorpromazine, haloperidol, etc.), or Tramadol or have taken them within the past 3 months.
  • Must not have experienced cardiac problems, fibrillation, or have taken medications associated with cardiac conditions within the past 3 months.
  • Must not meet the diagnostic threshold for Autism Spectrum Disorder, Intellectual Disability, or Psychotic Disorders.

Treatment and study plan

Sham device

Device

Intervention which uses an inactive form of stimulation via electrodes on the scalp.

STARSTIM Device in-phase

Device

Intervention that uses the Starstim tES device to introduce transcranial alternating current stimulation (tACS) in the form of in-phase theta (~3.5 to ~7.5 Hz) via electrodes on the scalp.

STARSTIM Device anti-phase

Device

Intervention that uses the Starstim tES device to introduce transcranial alternating current stimulation (tACS) in the form of anti-phase stimulation via electrodes on the scalp.

Primary outcomes

  1. The Difference Between Incidental Memory of Faces on Error versus Correct Trials from Baseline to Post Brain Stimulation

    Time frame: Baseline through study visit completion, a maximum of 3 hours

    The hit rate for faces that appeared on error trials minus the hit rate for faces that appeared on correct trials.

Sponsors and collaborators

Lead sponsor

Florida International University

Other

Registry information

Official study title

Effects of Non-Invasive Brain Stimulation on Task Performance

Acronym: STIM

Important dates

Study start
2026
Primary completion
2031
Study completion
2031
First posted
Mar 12, 2026
Registry last updated
Mar 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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