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Completed

NCT Number: NCT05902130

Symptoms of Acute Coronary Syndrome in Medical Regulation

The main objective was to analyze the impact of the gender of the attending physician in the differences in the management of ST+ ACS between men and women.

This study will be conducted in partnership with the interventional cardiology team of the CHR Metz-Thionville and SAMU (emergency call center) of Moselle, which has a detailed registry of coronary angiographies at the center. A retrospective observational study will be carried out over a "typical" period outside of covid at the CHR Metz Mercy (2021-2022) based on coronary angiographies performed in the context of ST+ ACS at the CHR of patients referred by the center 15.

The patient's medical record will be analyzed, going back to his call to the 15 via tape listening. The number of subjects required being calculated at 104 men and 104 women, these patients will be selected from the database of our cardiologist colleagues and we will match one man to one woman by comparing the delays of several items (1st medical contact, time of 1st ECG, medicalization or not, delay of call to the cardiologist, delay of coronary angiography...) according to the sex of the regulator. The consequences of a difference in management will be also evaluated by analyzing in-hospital mortality, mortality at 30 days of management, and functional sequelae at discharge (grades of dyspnea, disturbance of myocardial contractility, LVEF at discharge).

This study based on the differences in questioning according to the gender of the regulating physician would allow better identification of the factors that increase the delay in the management of ST+ ACS in women, and to find avenues of correction in order to limit the loss of opportunity for patients.

The patients included who are still alive will receive a notification of non-objection by mail.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHR Metz-Thionville/Hopital de Mercy

Metz, 57085, France

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patient with emergency coronary angiography for ST+ ACS
  • having made a call to the Emergency Center for the same reason

Exclusion criteria

  • non-real ST+ ACS

Treatment and study plan

symptoms of a myocardial infarction

Other

Analysis of the differences in symptoms of a myocardial infarction between a man and a woman

Primary outcomes

  1. Delay between the call to the emergency center and the first contact with a physician

    Time frame: End of the call to the emergency center, less than 10 min

    Delay (minutes:seconds)

Secondary outcomes

  1. Delay between the call to the emergency center and the first electrocardiogram

    Time frame: At hospital discharge, an average of 2 hours

    Delay (hours:minutes)

  2. Dispatch of a medical ambulance (Y/N)

    Time frame: End of the call to the emergency center, an average of 20 min

    Number (%)

  3. Delay between the call to the emergency center and the first coronary angiography

    Time frame: At hospital discharge, an average of 2 hours

    Delay (minutes)

  4. In-hospital mortality

    Time frame: 30 days after the call to emergency center

    Number (%)

  5. Day 30 mortality

    Time frame: 30 days after the call to emergency center

    Number (%)

  6. Left Ventricular Ejection Fraction

    Time frame: At hospital discharge, less than 30 days

    Percentage

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Régional Metz-Thionville

Other

Registry information

Official study title

Symptoms of Acute Coronary Syndrome in Medical Regulation: a Retrospective Study

Acronym: SCAST+

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Jun 13, 2023
Registry last updated
Dec 26, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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