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Completed

NCT Number: NCT07505368

SWT VERSUS EMFT IN KOA

The purpose of this study was to compare the effect of extracorporeal shock wave therapy and pulsed electromagnetic field in reducing pain, improving function, and increasing ROM in knee osteoarthritis patients.

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Key information

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The Outpatient Clinics, Faculty of Physical Therapy Suez Canal University

Ismailia, Egypt

About this study

Knee osteoarthritis is a prevalent and debilitating condition that affects millions of people worldwide. It is particularly common in older adults and is a major cause of disability and reduced quality of life. The disease is characterized by the progressive degradation of articular cartilage, leading to pain, stiffness, and impaired function. The prevalence of knee osteoarthritis has been reported to range between 22% to 39% globally, and in specific regions like India, it is approximately 28.7%.

Extracorporeal shock wave therapy has emerged as a promising non-invasive treatment for knee osteoarthritis. The advantages of extracorporeal shock wave therapy include its ability to alleviate pain and improve joint function. Studies have demonstrated that extracorporeal shock wave therapy can significantly reduce pain scores and enhance physical function in patients with knee osteoarthritis, making it a viable treatment option. Additionally, extracorporeal shock wave therapy has been shown to positively affect cartilage regeneration and reduce inflammation markers like matrix metalloproteinase-3, which is involved in cartilage degradation.

However, the disadvantages of extracorporeal shock wave therapy include the potential for adverse effects on articular cartilage, particularly at higher intensities, which may result in the worsening of cartilage conditions in some cases. Furthermore, while extracorporeal shock wave therapy is generally well-tolerated, its efficacy may vary depending on the energy levels used, with moderate intensity showing the best outcomes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Sixty patients must have a confirmed diagnosis of knee osteoarthritis, specifically those with mild to moderate osteoarthritis.
  • Participants must have experienced knee pain lasting more than 3 months.
  • Their ages will be ranged from 40 to 60 years.
  • Their body mass index within the range of 22.7 to 28.5 kg/m² kg/m².
  • Both male and female patients are eligible for the study.
  • At least two positive provocative tests, such as joint line tenderness and crepitus, which are commonly associated with knee osteoarthritis.

Exclusion criteria

  • Inflammatory arthritis (e.g., rheumatoid arthritis) or other forms of arthritis that are not osteoarthritis.
  • Undergone knee replacement surgery or any significant knee surgery within the past year.
  • Severe cardiovascular, respiratory, renal, or hepatic diseases that could interfere with study participation or outcomes.
  • Received intra-articular corticosteroid injections in the affected knee within the last 3 months.
  • Pregnant or breastfeeding due to the unknown effects of study treatments on fetal and infant development.
  • Neurological conditions affecting the lower limbs (e.g., stroke, neuropathy). body mass index greater than 30 kg/m², as severe obesity may influence treatment outcomes and complicate assessment.
  • Cognitive impairments or psychiatric conditions that may affect their ability to participate.

Treatment and study plan

Shock wave therapy

Procedure

Electrotherapy application

Electromagnetic Field Therapy

Procedure

Electrotherapy application

Conservative therapy

Procedure

Hot pack, stretching exercises and strengthening exercises

Primary outcomes

  1. Change in physical function.

    Time frame: Pretreatment measurement and posttreatment (4 weeks) measurement.

    Measurement of physical function using the Western Ontario and McMaster Universities Osteoarthritis Index.

  2. Change in pain intensity

    Time frame: Pretreatment measurement and posttreatment (4 weeks) measurement.

    Measurement of pain intensity using the visual analogue scale.

  3. Change in range of motion.

    Time frame: Pretreatment measurement and posttreatment (4 weeks) measurement.

    Measurement of range of motion using the digital goniometer.

Sponsors and collaborators

Lead sponsor

Suez Canal University

Other

Registry information

Official study title

SHOCK WAVE THERAPY VERSUS ELECTROMAGNETIC FIELD THERAPY IN KNEE OSTEOARTHRITIS

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Apr 1, 2026
Registry last updated
Apr 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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