Swiss Primary Sclerosing Cholangitis Cohort Study

Research project in which biological material is sampled and health-related personal data is further used and collected.

Coded data are used.

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Key information

Conditions

Cholangitis, Sclerosing Bile Duct Diseases Biliary Tract Diseases Cholangitis Digestive System Diseases PSC Primary Sclerosing Cholangitis (PSC)

Sex eligibility

All sexes

Study type

Observational

Primary location

Fondazione Epatocentro Ticino, Lugano, Canton Ticino, Switzerland

About this study

The investigators wish to collect high quality prospective data on a rare disease in order to elucidate epidemiology, natural history, response to treatment and outcome. In addition, a biobank allows addressing specific scientific issues on a variety of open questions. The cohort will provide a platform for carrying out scientific research projects on PSC. In addition, the cohort will allow collaborations with reference networks on PSC abroad

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients diagnosed with PSC according to established criteria (European Association for the Study of the Liver. EASL Clinical Practice Guidelines: management of cholestatic liver diseases) of any age. Patients not fulfilling such criteria but still diagnosed with PSC in a hepatology referral centre can be included
patients living in Switzerland

Exclusion criteria

Treatment and study plan

Primary outcomes

Disease course

Time frame: 3 years

Observing disease course
Disease features

Time frame: 3 years

Observing disease features in Swiss population and see if they are similar to other countries'
Response to treatment

Time frame: 3 years

Observing response to treatment
Overall survival

Time frame: 3 years

Observing overall survival
Transplantation-free survival rate

Time frame: 3 years

Observing transplantation-free survival rate

Study contacts

Contact information is provided by the study sponsor or research team.

Andreas Cerny, Prof. Dr. med

CONTACT

[email protected]

+41 91 910 6570

Sponsors and collaborators

Lead sponsor

Fondazione Epatocentro Ticino

Other

Registry information

Important dates

Study start: 2017
Primary completion: 2030
Study completion: 2030
First posted: May 10, 2017
Registry last updated: Aug 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting