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OpenTrials
Completed

NCT Number: NCT02046239

Suture vs Staples for Skin Closure After Liver Resection

Closure of the skin after liver resection (surgery to remove part of the liver) may be achieved by one of several methods. The standard method at our institution is to use stainless steel staples to adjoin the two sides of skin. Alternatively, a continuous absorbable suture may be used to "sew" the skin together.

The ideal method of closure should be safe, effective, associated with minimal patient discomfort and have a good cosmetic result. At present, there is no scientific evidence to describe which method is most suitable following liver resection.

The primary aims of this study is to investigate which method (subcuticular sutures vs staples) offers the best result in postoperative rate of (1) skin infection, (2) skin dehiscience (separation of skin) and (3) time taken to perform skin closure. In addition, we are interested in which method is best for patient satisfaction and cosmetic appearance and which method is most cost effective.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Leeds Teaching Hospital NHS Trust

Leeds, LS9 7TF, United Kingdom

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients undergoing liver resection surgery for benign or malignant aetiology
  • All patients undergoing surgery as a living liver donor.

Exclusion criteria

  • Any patient with an active wound infection
  • Any patient with an active incisional wound hernia from previous surgery
  • Synchronous bowel/liver surgery
  • History of keloid formation

Treatment and study plan

Suture Group

Procedure

Staple Group (control)

Biological

Primary outcomes

  1. Post-operative infection time

    Time frame: 1 year

Secondary outcomes

  1. Time taken for skin closure

    Time frame: 12 months

Sponsors and collaborators

Lead sponsor

The Leeds Teaching Hospitals NHS Trust

Other

Registry information

Official study title

A Randomised Controlled Trial to Compare Subcuticular Suture vs Staples for Skin Closure After Liver Resection.

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Jan 27, 2014
Registry last updated
Jul 8, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.