Survival Among Patients With Pancreatic Cancer Depending on Surgical Resection Rate

The primary aim of this population-based study is to investigate how a high resection rate of pancreaticoduodenectomy affects overall survival among patients aged ≥70 years with pancreatic ductal adenocarcinoma. The secondary aim is to determine if a high resection rate of pancreaticoduodenectomy increases perioperative morbidity.

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Key information

Conditions

Pancreatic Ductal Adenocarcinoma

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosed between 1 January 2010 and 31 December 2018
Registered in the Swedish National Registry for tumours in the pancreatic and periampullary region
Either a diagnosis of pancreatic ductal adenocarcinoma of the pancreatic head or having been resected with pancreaticoduodenectomy

Exclusion criteria

None

Treatment and study plan

Resection rates

Other

All groups are divided into one high- and one low resection rate group depending on percentage of patients with pancreatic ductal adenocarcinoma resected per county and year (first three groups) and resection rate of pancreaticoduodenectomy per 100 000 inhabitants per county (last three groups)

Primary outcomes

Overall survival

Time frame: A little more than 10 years (from first patient to vital status)

Overall survival among patients aged 70 years and over with pancreatic ductal adenocarcinoma in the pancreatic head

Secondary outcomes

Severe complications after pancreaticoduodenectomy

Time frame: Around 10 years (patients diagnosed between 1 January 2010 and 31 December 2018, latest dismissal from hospital january 2020)

The rate of severe complications among patients aged 70 years and over who had undergone pancreaticoduodenectomy for any reason

Sponsors and collaborators

Lead sponsor

Linkoeping University

Other Gov

Registry information

Official study title

Survival Among Elderly Patients in Sweden With Right-sided Pancreatic Adenocarcinoma Depending on Resection Rate of Pancreaticoduodenectomy

Important dates

Study start: 2010
Primary completion: 2020
Study completion: 2020
First posted: Mar 17, 2021
Registry last updated: Mar 17, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed