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OpenTrials
Completed

NCT Number: NCT03188926

Surgical Treatment of Long Bone Metastases

To provide treatment guidelines for patients with long bone metastatic disease based on observational study and to propose an algorithm to guide orthopedic surgeons in decision-making for these patient.

Completed

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Key information

Conditions

Bone Metastases Surgery

Sex eligibility

All sexes

Study type

Observational

Primary location

Istituto Ortopedico Rizzoli

Bologna, 40136, Italy

About this study

The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary fixation (IMN) or endoprosthetic reconstruction (EPR) with a specific focus on (1) the rate of complication or failure; (2) differences in complication rates by anatomic site; (3) functional results as assessed by the Musculoskeletal Tumor Society System (MSTS); (4) differences in complication rate between patients treated with INM versus EPR; and (5) differences in survival in patients with metastatic bone disease based on disease-specific, laboratory, and demographic information.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • bone metastases of the extremity

Exclusion criteria

  • bone metastases of the spine

Treatment and study plan

intramedullary fixation or endoprosthetic reconstruction

Procedure

Surgical treatment of impending or pathologic fracture in the extremities

Primary outcomes

  1. Clinical outcomes after treatment of long bone metastases with intramedullary nail versus endoprosthetic reconstruction

    Time frame: 1 year

    The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary nail versus endoprosthetic reconstruction with a specific focus on differences in complication rate between patients treated with intramedullary nail versus endoprosthetic reconstruction

Secondary outcomes

  1. Survival in patients undergoing surgery for metastatic bone disease

    Time frame: 1 year

    Provide a reliable and objective means of estimating survival in patients with metastatic bone disease based on disease-specific

Sponsors and collaborators

Lead sponsor

Istituto Ortopedico Rizzoli

Other

Registry information

Official study title

Surgical Treatment for Long Bone Metastases With Intramedullary Nail or Endoprosthetic Reconstruction

Acronym: MTC

Important dates

Study start
2016
Primary completion
2017
Study completion
2020
First posted
Jun 16, 2017
Registry last updated
Aug 4, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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