Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07079254

Surgical Outcome After Displaced Bucket-handle Meniscal Lesions - Repair Versus Partial Meniscectomy

The menisci of the knee joint are structures composed of cartilage and connective tissue, whose primary functions are to stabilize the joint and distribute weight across joint surfaces. In doing so, it helps protect the joint from osteoarthritis - a form of joint failure commonly referred to as "joint wear". Meniscal surgeries are among the most common orthopaedic procedures performed both in Sweden and globally. Historically, damaged menisci were treated by removing the injured part. However, this approach is linked to early-onset osteoarthritis. Osteoarthritis affects approximately one-third of individuals over the age of 45 and ranks among the ten most common diagnoses in Europe based on years lived with disability. The knee is the most frequently affected joint, and the importance of the menisci in preserving knee function has become increasingly recognized.

In recent years, advances in surgical techniques have led to a shift towards meniscus-preserving procedures. A typical injury is the displaced meniscus, in which a large portion of the meniscus becomes detached from the joint capsule and wedges itself inside the joint, causing mechanical locking and preventing full extension. A displaced meniscus often loses its blood supply and suffers mechanical damage from being compressed between the joint surfaces. To preserve the meniscus and prevent irreversible damage, early surgical intervention is required. If the injury is too old or the tissue too damaged, the injured part of the meniscus must be removed, which significantly increases the risk of developing early knee osteoarthritis.

It remains unclear how soon surgery must be performed to successfully preserve the meniscus, and this likely depends on various other factors, including patient age, presence of additional joint injuries, and surgical technique. There is currently no reliable data on the proportion of displaced menisci that heal after meniscus-preserving surgery. However, studies suggest that 20-30% of repaired menisci require reoperation due to failed healing.

Given that displaced menisci are considered surgical emergencies, they pose a significant burden on healthcare systems already strained by limited access to urgent surgery. Meanwhile, ongoing development of surgical techniques raise ethical and logistical questions for health providers - especially as the scientific evidence for the benefits of some advanced treatments remains inconclusive.

Therefore, more research is needed to guide the optimal management of displaced bucket-handle lesions across a diverse patient population, taking into account age, activity level, and concurrent injuries. A key priority is to identify predictors of healing potential, particularly the time window during which surgical repair remains a viable option. With better knowledge, more menisci could potentially be preserved - reducing both the number of unnecessary re-operations and the long-term incidence of knee osteoarthritis.

Recruiting

Interested in participating?

Request Info

Key information

Age range

15 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Region Skåne, Orthopaedic department Kristianstad/Hässleholm, Hässleholm, Skåne County, Sweden

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 15 years or above.
  • Displaced longitudinal bucket-handle tear including the posterior horn on MRI and a knee extension deficit.

Exclusion criteria

  • Patient younger than 15 years.
  • Insufficient knowledge of the Swedish language.
  • Per-operative findings including a bucket-handle rupture in combination with a complete radial rupture

Treatment and study plan

Meniscus suture

Procedure

The meniscus bucket-handle injury will either be treated with meniscus suture or partial meniscectomy

Partial meniscectomy

Procedure

The meniscus bucket-handle injury wil be treated with either meniscus suture or partial meniscectomy

Primary outcomes

  1. Re-operation

    Time frame: 2-10 years

    Re-operation for meniscus injury/lesion

Secondary outcomes

  1. Knee Injury and Osteoarthritis Outcome Score (KOOS)

    Time frame: From 6 months to 10 years

    Patient reported outcome measure in the form of Knee Injury and Outcome Score (KOOS). A total score, called KOOS4, without the ADL scale, will be calculated. The scale ranges from 0 (worst) to 100 (best).

  2. Osteoarthritis in the knee

    Time frame: 10 years

    Radiological osteoarthritis

Study contacts

Contact information is provided by the study sponsor or research team.

Ola Svejme, MD, PhD

CONTACT

[email protected]

+46 722-106158

Sofie Alerskans, MD

CONTACT

[email protected]

+46 768-487639

Sponsors and collaborators

Lead sponsor

Region Skane

Other

Registry information

Official study title

Surgical Outcome After Displaced Bucket-handle Meniscal Lesions - Repair Versus Partial Meniscectomy: A 10-year Observational Study

Important dates

Study start
2023
Primary completion
2035
Study completion
2045
First posted
Jul 22, 2025
Registry last updated
Jul 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.