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OpenTrials
Completed

NCT Number: NCT04709718

Surgical Management of Giant Hepatic Hemangioma

Hepatic hemangiomas are the commonest benign mesenchymal lesions of the liver. Most of these lesions are asymptomatic. Giant hepatic hemangiomas (GHH) (> 10 cm) are often symptomatic and require surgical intervention. This study aimed to describe the clinical findings, risk factors, diagnostic approach and management of GHH.

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Key information

Conditions

Age range

15 year–90 year

Sex eligibility

All sexes

Study type

Observational

About this study

Hepatic hemangiomas are the most common benign tumors of the liver with the incidence of 0.4 to 20% . They are most often discovered incidentally on imaging studies. Typical hemangiomas usually do not increase in size over time and therefore are unlikely to cause symptoms. Giant hepatic hemangiomas (GHH) are defined as hemangiomas larger than 5 cm . They are usually responsible for overt clinical symptoms and complications consisting, most often, of upper abdominal pain, hemorrhage, biliary compression, or a consumptive coagulopathy that may require prompt surgical intervention or other treatments . Management of liver hemangiomas ranges from close observation to surgery depending upon the site, size and symptoms .

It is widely accepted that intervention is indicated only for symptomatic hemangiomas. Surgical resection is indicated in patients with abdominal complaints or complications, or when diagnosis remains inconclusive. The ideal surgical treatment for GHH is still controversial. Enucleation is the preferred surgical method based on the existing literature. In this study, we report our 17-year experience of clinical management of GHH.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Radiological diagnosis of geant liver hamangioma.

Exclusion criteria

  • Radiological diagnosis of liver hemangioma less than 10cm.

Treatment and study plan

Hepatectomy

Procedure

liver resection taking over the liver hemangioma

Primary outcomes

  1. number of patient getting good result after surgery

    Time frame: 1 year

    patient asymptomatic after surgery or not

Sponsors and collaborators

Lead sponsor

Université de Sousse

Other

Collaborators

  • Sahloul Hospital of Sousse

Registry information

Official study title

Surgical Management of Giant Hepatic Hemangioma: a 10-year Single Center Experience

Important dates

Study start
2008
Primary completion
2019
Study completion
2020
First posted
Jan 14, 2021
Registry last updated
Jan 14, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.