Surgical Management of Cesarean Scar Ectopic Pregnancy: Hysteroscopy & Laparoscopy Outcomes

The study investigates the feasibility, safety, and outcomes of a simultaneous surgical approach for cesarean scar ectopic pregnancy (CSEP). CSEP is a prevalent and serious form of ectopic pregnancy requiring swift intervention. The research explores using hysteroscopy and laparoscopy concurrently to manage the CSEP and repair the uterine scar defect. The procedure involved hysteroscopic-guided evacuation and a double-layer laparoscopic repair, followed by a second hysteroscopy to confirm the repair's effectiveness.

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Key information

Conditions

Cesarean Section Complications

Age range

25 year–55 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Banha University

Banhā, El- Qalyobia, 13511, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with positive clinical and lab pregnancy diagnosis;
Patients with history of at least one previous Cesarean section;
Patients with Transvaginal ultrasound documenting Cesarean scar ectopic Pregnancy;

Exclusion criteria

Patients with were extensive adhesions between the mass and the urinary bladder on MRI;
Patients with myomas, polyps, endometrial hyperplasia, and cancers of the cervix or endometrium;
Patients with a body mass index (BMI) of >35kg/m2;
Patients with previous abdominal surgeries with possible difficulties during laparoscopy;
Patients with menstrual irregularities, or coagulation disorders.

Treatment and study plan

Hysteroscopy

Procedure

Hysteroscopic-guided suction evacuation and double-layer laparoscopic repair of the niche were performed concomitantly and followed by second-look hysteroscopy to ensure the competence of the repair.

Primary outcomes

Success Rate of Hysteroscopy in Restoring the normal endometrial metrics, and removing any uterine defects.

Time frame: 6~7 months

The proportion of patients who restored their normal endometrial metrics and removed any uterine scars during the study, reflecting the effectiveness of the applied Hystreoscopy regimens.

Sponsors and collaborators

Lead sponsor

Benha University

Other

Registry information

Official study title

Surgical Outcomes of Simultaneous Hysteroscopy/Laparoscopy for Cesarean-Section Niche Ectopic Pregnancy Management and Uterine Niche Repair

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Jul 31, 2025
Registry last updated: Jul 31, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed