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Completed

NCT Number: NCT07180199

Surgical Correction of V Pattern Intermittent Exotropia Without Inferior Oblique Muscle Overaction

Evaluation of the results of surgical correction of V pattern intermittent exotropia without inferior oblique muscle overaction by either performing bilateral lateral rectus recession (BLR) alone or performing bilateral lateral rectus recession asssosiated with upward transposition of lateral rectus muscle insertion

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Key information

Age range

5 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tanta University

Tanta, El-Gharbia Governorate, Egypt, 31527, Egypt

About this study

Intermittent exotropia (IXT) is the most common type of strabismus which is a disorder of binocular eye movement control in which one eye intermittently moves outwards.Intermittent exotropia may be associated with difference in the horizontal deviation from the primary position to the upward or downward gaze giving A or V pattern In V-pattern intermittent exotropia (XT), there is an increase in the horizontal deviation as the eyes move from downgaze to upgaze.

Non-surgical treatment includes correction of refractive error, orthoptics, overcorrecting minus lenses and prismotherapy. Surgical options includes unilateral medial rectus muscle resection combined with a lateral rectus muscle recession or bilateral lateral rectus recession as in basic type IXT OR bilateral lateral rectus muscle recession as in divergent excess type OR bilateral medial rectus muscle resection as in convergence insufficiency.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with V pattern intermittent exotropia (XT increasing by >10Δ in upgaze compared with Downgaze).
  • No or minimal inferior oblique overaction on both sides (+1)
  • Minimum follow-up period of 6 months after surgical correction of strabismus

Exclusion criteria

  • Structural eye pathology.
  • Significant neurodevelopmental delay.
  • ntermittent exotropia without V pattern.
  • Superior oblique under action.
  • Duane syndrome.
  • Less than 6 months follow up.

Treatment and study plan

Bilateral Lateral Rectus Recession (BLR Recession)

Procedure

This procedure involved recession of both lateral rectus muscles to reduce large-angle exotropia.

Bilateral Lateral Rectus Recession with Upward Transposition

Procedure

This procedure involved bilateral lateral rectus recession combined with upward transposition of the insertion to enhance ocular alignment in patients with large-angle exotropia.

Primary outcomes

  1. Angle of Ocular Deviation

    Time frame: 6 months postoperatively

    The degree of ocular misalignment was measured using prism cover test at near and distance fixation. Successful outcome was defined as residual deviation ≤10 prism diopters.

Secondary outcomes

  1. Postoperative Complications

    Time frame: 6 months postoperatively

    Complications such as overcorrection, undercorrection, or limitation of ocular motility were recorded.

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Evaluation of the Results of Surgical Correction of V Pattern Intermittent Exotropia Without Inferior Oblique Muscle Overaction

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Sep 18, 2025
Registry last updated
Sep 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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