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OpenTrials
Active, Not Recruiting

NCT Number: NCT07435025

Surgery for Obstructed Gastric Carcinoma

The goal of this clinical trial is to find the best treatment for obstructed gastric carcinoma in gastric cancer patients. It will include all patients with obstructed gastric cancer with different ages and sex who consented to share in the trial. The main question is what is the better for management for obstructed gastric cancer; palliative resection or palliative bypass? We hypothesized that resection is better. patients will be divided into two groups. the primary outcome measure will be the relief of obstruction

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Gastric Cancer Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Neoplasms Neoplasms by Site Stomach Diseases Stomach Neoplasms

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

faculty of medicine, Zagazig University

Zagazig, Sharqia Province, 44519, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • emergency obstructed gastric cancer patients

Exclusion criteria

  • non obstructed gastric cancer patients

Treatment and study plan

palliative gastric resection

Procedure

distal, subtotal or total gastrectomy with gastro-jejunostomy or eosphago-jejunostomy will be done

palliative bypass

Procedure

palliative gastro-jejunostomy or eosphago-jejunostomy will be done

Primary outcomes

  1. upper gastrointestinal symptoms

    Time frame: from one day to two weeks after surgery

    upper gastrointestinal symptoms will be evaluated after surgery by Rhodes Index questionnaire. It is a validated, self-report instrument used to measure the intensity, frequency, and distress of upper gastrointestinal symptoms. The scale measures three main areas: nausea (frequency, duration, distress), vomiting (amount, frequency, distress), and retching (frequency, distress). It utilizes a 5-point Likert scale (0-4) to quantify the severity of these symptoms. 0 is the least amount of distress and 4 is the most distress.

Secondary outcomes

  1. anastmotic leak

    Time frame: from day one to two weeks after surgery.

    anastmotic site leakage will be assessed by abnormal discharge in the drain calculated in cc.

  2. ICU admission

    Time frame: from day one to two weeks after surgery

    the need of ICU admission will be evaluated by (yes or No)

  3. wound infection

    Time frame: from day one to one month after surgery

    wound infection will be identified by presence of pus in the dressing and positive culture and sensitivity test

  4. mortality

    Time frame: from one day to one month after surgery

    follow up of patient after surgery (died or not)

Sponsors and collaborators

Lead sponsor

Zagazig University

Other Gov

Registry information

Official study title

Palliative Resection Versus Palliative Bypass in Obstructed Locally Advanced Gastric Carcinoma

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Feb 27, 2026
Registry last updated
Feb 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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