Super-Resolution Ultrasound of the Brain in 3D

Inclusion criteria

• Patient aged 18 and over
• Hospitalized patient with ischemic stroke in the deep territory of the middle cerebral artery
• Patient with lesion observable on MRI
• Patient included between 24 hours and 7 days after the ischemic stroke
• Patient with a temporal window which allows soundproofing of the polygon of Willis and the middle cerebral artery
• Patient having signed free, informed and written consent
• Patient affiliated to a social security system (excluding AME)

Exclusion criteria

• Contralateral middle cerebral artery territory stroke or contralateral middle cerebral artery occlusion
• Patient with contraindication to Doppler ultrasound with contrast (right-left shunt, severe pulmonary arterial hypertension)
• Patient with hypersensitivity to the active princip of Sonovue (sulfur hexafluoride) or these excipients
• Patient with uncontrolled systemic hypertension
• Patient with respiratory distress syndrome
• Patient under guardianship or curatorship
• Pregnant or breastfeeding patient (positive blood pregnancy test during hospitalization)
• Patient with damaged skin at the temporal level
• Patient having presented in the 7 days preceding inclusion an acute coronary syndrome or suffering from unstable ischemic heart disease