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Completed

NCT Number: NCT07517003

Sunflower and Olive Oils for Preventing Diaper Dermatitis in Hospitalized Infants

This quasi-experimental study aimed to evaluate the effects of sunflower oil and olive oil on the development of diaper dermatitis in hospitalized infants receiving antibiotic therapy. Infants aged 0-24 months were assigned to sunflower oil, olive oil, and control groups. Oils were applied to the diaper area after each diaper change. Infants were followed daily for 3-7 days, and diaper dermatitis severity was assessed using a four-stage clinical classification. The incidence of diaper dermatitis was compared between groups.

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Key information

Age range

0 month–24 month

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Midyat State Hospital

Midyat, Mardin, 47500, Turkey (Türkiye)

About this study

Diaper dermatitis is a common skin condition in infants and occurs more frequently in hospitalized infants receiving systemic antibiotics. This quasi-experimental study evaluated the preventive effects of sunflower oil and olive oil on diaper dermatitis. The study included 150 infants aged 0-24 months hospitalized and receiving antibiotic therapy. Participants were assigned to three groups: sunflower oil, olive oil, and control. In the intervention groups, oils were applied to the diaper area after each diaper change, while the control group received routine care. Infants were followed daily for 3-7 days, and diaper dermatitis severity was assessed using a four-stage clinical classification. The primary outcome was the incidence of diaper dermatitis. The study aimed to determine whether sunflower oil and olive oil reduce diaper dermatitis in hospitalized infants.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Infants aged 0-24 months
  • Hospitalized and receiving systemic antibiotic therapy
  • Expected hospital stay of 3-7 days
  • Using disposable diapers
  • Written informed parental consen

Exclusion criteria

  • Premature or low birth weight infants
  • Existing diaper dermatitis
  • Diarrhea or oral candidiasis
  • Chronic skin diseases (eczema, atopy, seborrheic dermatitis)
  • Receiving antifungal treatment
  • Neurological or urological anomalies
  • Use of urinary catheter or bag
  • Toilet-trained infants

Treatment and study plan

Sunflower Oil

Other

Sunflower oil applied to the diaper area after each diaper change during hospitalization.

olive oil

Other

Olive oil applied to the diaper area after each diaper change during hospitalization.

Routine care

Other

Routine diaper care without topical oil application during hospitalization.

Primary outcomes

  1. Incidence of diaper dermatitis

    Time frame: During hospitalization (3 days up to 7 days)

    Incidence of diaper dermatitis assessed using diaper dermatitis severity scoring system in hospitalized infants receiving sunflower oil, olive oil, or routine care.

Secondary outcomes

  1. Severity of diaper dermatitis

    Time frame: During hospitalization (3-7 days)

    Severity of diaper dermatitis assessed daily using diaper dermatitis severity scoring system in hospitalized infants.

Sponsors and collaborators

Lead sponsor

Dicle University

Other

Registry information

Official study title

The Effect of Sunflower and Olive Oils on Diaper Dermatitis in Hospitalized Infants Treated With Antibiotics: A Quasi-Experimental Study

Acronym: DD-OIL

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Apr 8, 2026
Registry last updated
Apr 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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