Succinylcholine : 1mg/kg
DrugOther names: Suxaméthonium Aguetant®, SUXAMETHONIUM BIOCODEX 50 mg/ml, solution injectable
NCT Number: NCT02000674
All adult patients with spontaneous cardiac activity and requiring tracheal intubation in the pre hospital emergency context will be included in order to compare the use of succinylcholine vs Rocuronium for prehospital emergency intubation.
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Notify Me18 year and older
All sexes
Interventional
Phase 3
CHU de La Réunion, Saint-Denis, La Réunion, France
All adult patients with spontaneous cardiac activity and requiring tracheal intubation in the pre hospital emergency context will be included. All intubation will be performed by an emergency physician or a nurse specialized in anesthesia. For patients with spontaneous cardiac activity, rapid sequence intubation will be performed to allow intubation.
Comparisons studied will be : Intubation success rate at the first laryngoscopy, glottis exposure assessed by Cormack and Lehane classification, difficult intubation rate assessed by the Intubation Difficult Score (IDS), the conditions of intubation assessed by the Copenhagen score, the need for alternative airway techniques and the immediate post intubation complications rate as vomiting, dental trauma, pulmonary inhalation, arterial desaturation , hypotension episodes and cardiac arrest occurrence.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Other names: Suxaméthonium Aguetant®, SUXAMETHONIUM BIOCODEX 50 mg/ml, solution injectable
Other names: ESMERON®
Time frame: between 1 hour to 3 hours after inclusion
Measured by the proportion of successful intubation in the first laryngoscopy.
Time frame: between 1 hour to 3 hours after inclusion
measured by the Intubation Difficulty Scale
Time frame: between 1 hour to 3 hours after inclusion
using the Copenhagen score
Time frame: between 1 hour to 3 hours after inclusion
Time frame: between 1 hour to 3 hours after inclusion
complications : esophageal intubation, mainstem intubation, vomiting, pulmonary aspiration, dental trauma, bronchospasm or laryngospasm, ventricular tachycardia, arterial desaturation, hypotension, or cardiac arrest
Centre Hospitalier Universitaire de la Réunion
Other
Succinylcholine vs Rocuronium for Prehospital Emergency Intubation : a Randomized Trial
Acronym: CURASMUR
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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