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NCT Number: NCT06309511

Subendocardial Viability Ratio in Hypertension

The aim of the research is to evaluate the Subendocardial Viability Ratio (SEVR) in hypertensive patients, using non-invasive arterial tonometry, and to establish the influencing factors and the possibility of predicting cardiovascular morbidity and mortality in arterial hypertension.

The SEVR will be evaluated on all patients belonging to the Arterial Hypertension Centers undergoing non-invasive arterial tonometry.

The SEVR is calculated on the morphology of the central pressure wave as the ratio between the DPTI (diastolic pressure-time index), i.e. the area between the carotid pressure curve and the ventricular pressure curve during the diastolic phase, and the SPTI ( systolic pressure-time index), i.e. the area under the carotid pressure curve during the systolic phase.

The SEVR will be correlated with the anthropometric and pathology variables which will be collected in an appropriate database.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Centro di Prevenzione e Cura dell'Ipertensione Arteriosa "Alessandro Filippi", Mascalucia, Catania, Italy

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Hypertension

Exclusion criteria

  • Atrial fibrillation

Treatment and study plan

Arterial tonometry

Diagnostic Test

Arterial transcutaneous tonometry

Primary outcomes

  1. Buckberg index

    Time frame: At recruitment, at 1 year, 2 years, 3 years and 4 years of follow-up

    Assessment of subendocardial viability ratio (SEVR)

Study contacts

Contact information is provided by the study sponsor or research team.

Paolo Salvi, MD

CONTACT

[email protected]

+390261911 ext. 2968

Sponsors and collaborators

Lead sponsor

Istituto Auxologico Italiano

Other

Registry information

Acronym: SEVR-HT

Important dates

Study start
2022
Primary completion
2026
Study completion
2026
First posted
Mar 13, 2024
Registry last updated
Aug 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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