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NCT Number: NCT07270354

STUMBL vs TTSS in Predicting Morbidity and Mortality of Blunt Chest Trauma

This study aim to compare the effectiveness of the STUMBL Score and the Thoracic Trauma Severity Score (TTSS) in predicting morbidity and mortality in patients with blunt chest wall trauma, and to evaluate which scoring system provides greater clinical utility for early risk stratification and management decisions.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

Blunt chest wall trauma poses a clinical challenge due to its substantial contribution to morbidity and mortality, particularly following falls and vehicular accidents. Early identification of patients at high risk of complications is critical yet difficult, as delayed respiratory issues often escape initial detection. Traditional trauma scoring systems (e.g. ISS, AIS) lack specificity for isolated thoracic injury, creating a niche for more focused prognostic tools.

Two promising models have emerged: the STUMBL Score-based on age, number of rib fractures, chronic lung disease, pre-injury anticoagulant use, and oxygen saturation-is explicitly designed for blunt chest trauma prognosis. Studies report strong discriminatory performance, with development-phase c-index up to 0.96 . External validations vary: one UK cohort showed STUMBL ≥ 11 had a sensitivity of 79%, specificity of 78%, and AUC of 0.84-comparable to clinician judgment ; Italian data demonstrated excellent discrimination (C-index ~0.90) and calibration .

The Thoracic Trauma Severity Score (TTSS), initially validated in polytrauma ICU patients, yields moderate to good discrimination (c-indices 0.72-0.85) across validation studies .

Though these scores show promise, high methodological bias and limited external validations temper their widespread adoption . A direct, comparative analysis of STUMBL and TTSS within a well-defined patient cohort is thus needed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients (≥18 years) presenting with blunt chest trauma.
  • Patients who have given written informed consent to participate in the study

Exclusion criteria

  • Penetrating chest injuries
  • Pediatric patients (<18 years)
  • Patients with incomplete records or who decline consent
  • Pregnant women
  • Disturbed conscious patients
  • Mechanically ventilated patients
  • Polytrauma patients

Treatment and study plan

Chest X-Ray

Diagnostic Test

First-line imaging for suspected rib fractures, hemothorax, pneumothorax, or pulmonary contusion

Computed Tomography (CT) Chest (with or without contrast)

Diagnostic Test

Gold standard for detecting:

Rib fractures (especially multiple and posterior).

Pulmonary contusions and lacerations.

Hemothorax, pneumothorax, hemopericardium.

Pleural or mediastinal injuries

Primary outcomes

  1. To compare the predictive accuracy of the STUMBL score and TTSS in forecasting morbidity and mortality in patients with blunt chest trauma

    Time frame: 14 day duration follow-up after ED admission

Secondary outcomes

  1. Easy of use of STUMBL score and TTSS score in emergency clinical settings

    Time frame: 14 day duration follow-up after ED admission

    How measured:

    Completion time measured with a stopwatch (minutes)

  2. To correlate each score with specific outcomes such as pneumonia, need for mechanical ventilation, ICU admission, and in-hospital mortality

    Time frame: 14 day duration follow-up after ED admission

Study contacts

Contact information is provided by the study sponsor or research team.

Mohamed Emad Ahmed Swefy, M.B.B.Ch

CONTACT

[email protected]

+201061845700

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

STUMBL (Study of the Management of Blunt Chest Wall Trauma) vs TTSS (Thoracic Trauma Severity Score) in Prediction of Morbidity and Mortality Rate of Blunt Chest Trauma

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 8, 2025
Registry last updated
Dec 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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