Studying the Analgesic Mechanism of the "Cough-trick"

The aim of the trial is to study the possible mechanism of the pain reducing effect of CT at peripheral venipuncture

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Key information

Conditions

Pain Acute Pain Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms Venipuncture

Age range

20 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male volunteers aged 20-40 years, height 165-190 cm.
Physical status I according to American Society of Anesthesiologists (ASA) classification.
Straight run of the vein on the dorsum of the non-dominant hand at least 4 cm long and 3 mm thick
No analgesics, anticoagulants and/or antiplatelet agents, sedatives or alcohol

Exclusion criteria

History of peripheral neuropathy
Abnormal skin conditions (infection, scars, psoriasis, eczema)
Unsuccessful venipuncture
Inflamed site of VP within 1 week after VP

Treatment and study plan

Venipuncture with "cough-trick"

Procedure

Primary outcomes

Pain intensity measured on 100 mm Visual Analogue Scale scale (VAS-100) where 0 = no pain and 100 = maximal pain

Time frame: immediately during venipuncture

Secondary outcomes

Heart rate, beats per minute

Time frame: 5 min during venipuncture

Sponsors and collaborators

Lead sponsor

University Medicine Greifswald

Other

Registry information

Official study title

Studying the Analgesic Mechanism of the "Cough-trick" - Randomized Crossover Volunteer Study

Important dates

Study start: 2004
Primary completion: 2008
Study completion: 2008
First posted: Oct 6, 2005
Registry last updated: Jun 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed