Tasurgratinib
DrugTasurgratinib oral tablet.
NCT Number: NCT04271488
The primary purpose of the study is to evaluate the effects of mild and moderate hepatic impairment on PK of tasurgratinib after a single dose administration.
Interested in participating?
Request Info20 year–79 year
All sexes
Interventional
Phase 1
Eisai Trial Site #6, Hakata, Fukuoka, Japan
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Key Exclusion for all Participants:
Additional Exclusion Criteria for Hepatically Impaired Participants (Cohorts A and B)
In addition to the Exclusion Criteria above for all participants, other standard exclusion criteria for participants with hepatic impairment will be used. These include:
Additional Exclusion Criteria for Healthy participants (Cohort C)
In addition to the Exclusion Criteria for all participants, other standard exclusion criteria for healthy participants in Phase 1 studies will be used. These include:
Tasurgratinib oral tablet.
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Time frame: Day 1: 0-144 hours postdose
Contact information is provided by the study sponsor or research team.
Eisai Co., Ltd.
Industry
An Open-label Parallel-Group Study to Evaluate Pharmacokinetics of E7090 and Its Metabolite in Subjects With Mild and Moderate Hepatic Impairment Compared to Healthy Subjects
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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