Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT06754865

Study to Evaluate the Clinical Value and Safety of Xiyanping Injection in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease(COPD) Based on Real-world Clinical Data

The primary objective is to evaluate the effect of Xiyanping injection on the treatment course of intravenous antibiotics for acute exacerbation of chronic obstructive pulmonary disease based on real-world clinical data, and to provide guidance and basis for the clinical application of Xiyanping injection combined with antibiotics in the treatment of acute exacerbation of chronic obstructive pulmonary disease.The secondary objectives is to evaluate the effect of Xiyanping injection on the indicators of acute exacerbation of inflammation and symptom improvement of chronic obstructive pulmonary disease.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Discharged with chronic obstructive pulmonary disease;
  • Hospitalized patients with COPD or AECOPD combined with lower respiratory tract infection;
  • The treatment course of Xiyanping injection in the exposed group was ≥3 days, and the non-exposed group did not use Xiyanping injection;
  • Study patients with complete medical records.

Exclusion criteria

  • Researchers believe that multiple proprietary Chinese medicines with the same or similar functions (such as Tanreqing injection, Reduning injection, Yanhuning injection, etc.) have been used at the same time during treatment, resulting in no assessment of efficacy or safety;
  • Patients with viral pneumonia or other systemic infection (such as urinary tract infection);
  • Patients who do not use intravenous antibiotics;
  • Refuse the case to be used by researchers.

Treatment and study plan

Xiyanping injection+ antibiotic

Drug

Xiyanping injection+ antibiotic

Antibiotic

Drug

Antibiotic

Primary outcomes

  1. Course of intravenous antibiotics

    Time frame: baseline, at 3(±1), 7(±1), and 10 days during medication

    Duration of intravenous antibiotic use

Study contacts

Contact information is provided by the study sponsor or research team.

Xiyuan Hospital of China Academy of Chinese Medical Sciences

CONTACT

010-62835646

Sponsors and collaborators

Lead sponsor

Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Industry

Registry information

Official study title

A Muulticenter, Open, Non-interventional, Retrospective Cohort Study to Evaluate the Clinical Value and Safety of Xiyanping Injection in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease(COPD) Based on Real-world Clinical Data

Acronym: XYP-202401

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jan 1, 2025
Registry last updated
Jan 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.