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Completed

NCT Number: NCT01766596

Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Montrachet Cohort)

The aim of the study proposed in Dijon is above all to focus on the possible relationship between age-related ocular pathologies (AMD and glaucoma) and et les degenerative neurological and cardiac pathologies.

The principal objective is to seek in subjects who have undergone cerebral MRI and echocardiography, associations between the thickness of postganglionic fibers measured by Optical Coherence Tomography at the 7th year (n=1500) and signs of cerebral impairment (psycho-cognitive tests, circulation time, MRI signs). This association will be studied after taking into account the principal environmental (particularly dietary) and genetic risk factors.

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Key information

Conditions

AMD Eye Diseases Glaucoma Ocular Hypertension

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU Dijon

Dijon, 21000, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Persons who have given their written consent
  • Persons who are taking part in the Dijon 3C study

Exclusion criteria

  • Persons who are not registered with social security agency
  • Persons who are unable to sit upright during a consultation

Treatment and study plan

Optical Coherence Tomography

Procedure

Primary outcomes

  1. Measure the mean thickness of postganglionic fibers

    Time frame: T=7 years of the 3C cohort

    Measure the thickness of postganglionic fibers by Optical Coherence Tomography in the 4 quadrants of the peripapillary sclera.

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire Dijon

Other

Registry information

Official study title

Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Montrachet Cohort): Seek Correlations Between Signs of Neurological and Vascular Degeneration and Signs of Ocular Aging

Acronym: 3C

Important dates

Study start
2009
Primary completion
2013
Study completion
2019
First posted
Jan 11, 2013
Registry last updated
May 1, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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