Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure

Electrical impedance tomography (EIT) is a non-invasive, bedside monitoring technique that provides continuous, real-time information about the regional distribution of the ventilation.

There are very few data in children admitted to the PICU (pediatric intensive care unit) and the aim of the study is to describe the distribution of the ventilation in children with acute respiratory failure and to study the impact of the interventions in the PICU (change in ventilatory settings, change in position, suction, respiratory kinesiotherapy,…)

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Acute Respiratory Failure

Age range

0 year–18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hôpital Femme Mère Enfant Service de néonatologie et réanimation néonatale, Bron, Rhone, France

About this study

Children with acute respiratory failure admitted to the PICU (pediatric intensive care unit)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Groupe A

children < 18 years
Admitted to the PICU with acute respiratory failure
Monitoring with EIT
non opposition of parents or legal representative Groupe B
children < 18 years
With general anesthesia and mechanical ventilation
Monitoring with EIT
non opposition of parents or legal representative

Exclusion criteria

Monitor not available
contra indication to the use of thoracic belt
Intraoperative period with use of electrocautery
Child not affiliated to a social security system and under protective measures legal

Treatment and study plan

Electrical impedance tomography

Procedure

All change in ventilator settings (mode, tidal volume or inspiratory pressure, Peep, recruitment…)

Primary outcomes

Distribution of Ventilation

Time frame: up to 48 hours

Distribution of ventilation as determined by changes in impedence in region of interest

Study contacts

Contact information is provided by the study sponsor or research team.

Florent Baudin, MD

CONTACT

[email protected]

04 72 12 97 05 ext. +33

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure: Impact of Intervention

Acronym: PELUCHE1

Important dates

Study start: 2022
Primary completion: 2027
Study completion: 2027
First posted: Apr 26, 2022
Registry last updated: Jan 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting