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NCT Number: NCT07678788

Study on the Association Between Serrated Polyps and Metachronous Advanced Colorectal Neoplastic Lesions

This study aims to explore the risk factors associated with the development of ACN and same-site ACN in patients with SP, thereby informing the optimization of clinical surveillance strategies

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Key information

Conditions

Sessile Serrated Lesion Serrated Polyp

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients aged > 18 years;At least one SP detected during the index colonoscopy and pathologically confirmed as TSA or SSL (according to the 2019 WHO classification criteria);Underwent complete polypectomy during the index colonoscopy;Received regular follow-up at Changhai Hospital, with an interval of ≥ 6 months between the index and follow-up colonoscopies;Complete clinical and pathological data.

Exclusion criteria

  • Incomplete colonoscopy or failed cecal intubation;Inadequate bowel preparation, defined as a Boston Bowel Preparation Scale (BBPS) score < 6 or a score < 2 in any bowel segment;Withdrawal time < 6 minutes;Diagnosis of hereditary cancer syndromes, such as familial adenomatous polyposis (FAP) or Lynch syndrome;Concurrent inflammatory bowel disease (IBD) or indeterminate colitis;History of colorectal cancer or other malignancies;Incomplete clinical or pathological records.

Treatment and study plan

Primary outcomes

  1. The occurrence of metachronous ACN

    Time frame: At least 6 months after index colonoscopy

Study contacts

Contact information is provided by the study sponsor or research team.

Yu Bai, M.D

CONTACT

[email protected]

+8619280762294

Sponsors and collaborators

Lead sponsor

Changhai Hospital

Other

Registry information

Official study title

Risk Factors for Metachronous Advanced Colorectal Lesions After Endoscopic Resection of Serrated Lesions

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 1, 2026
Registry last updated
Jul 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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