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Completed

NCT Number: NCT02634242

Study on the Antiaging Effect of Chinese Herb Drink

The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.

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Key information

Conditions

Gynecological Disorders Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Urogenital Diseases

Age range

20 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Background: Si-Wu-Tang (SWT) is a well-known traditional Chinese medicine (TCM) and widely used for treating various gynecological disorders. The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.

Methods: Sixty healthy voluntary subjects were recruited and assigned into two groups, who drank 125 mL of placebo (n=30) or SWT (n=30) for 6 continuous days per month during the following 6 months and vice versa with one month of washout period in between. During the initial, 3rd, 6th, 10th, and 13th months anthropometric measurements were performed as well as fasting blood samples were drawn for various biochemical assays. Abdominal ultrasonic and skin examination were performed at the initial, 6th and 13th months.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy adults

Exclusion criteria

  • exclusion criteria were history of smoking, alcoholism
  • pregnant or lactating women,
  • chronic diseases, hepatic or renal dysfunction.

Treatment and study plan

Si-Wu-Tang (SWT)

Other

The purpose of the current study was to check the physiological improvement of SWT on liver and skin and also the antioxidation in healthy adults.

Other names: Si-Wu-Tang (SWT) is a Traditional Chinese Medicine formula

Placebo

Other

The purpose of the current study was to check the physiological improvement of placebo on liver and skin and also the antioxidation in healthy adults.

Primary outcomes

  1. Total thiobarbituric acid reactive substances (TBARS)

    Time frame: 6 months

Secondary outcomes

  1. Glutathione content (GSH)

    Time frame: 6 months

  2. Total antioxidant capacity (TEAC)activities.

    Time frame: 6 months

  3. Superoxide dismutase (SOD) activity

    Time frame: 6 months

  4. GPx and glutathione reductase (GR) activity

    Time frame: 6 months

  5. Catalase

    Time frame: 6 months

  6. Glutamic oxaloacetic transaminase (GOT)

    Time frame: 6 months

  7. Glutamic pyruvic transaminase (GPT)

    Time frame: 6 months

Other outcomes

  1. Skin sebum content

    Time frame: 6 months

  2. Skin hydration

    Time frame: 6 months

  3. Skin surface water loss

    Time frame: 6 months

  4. Skin melanin index

    Time frame: 6 months

  5. Skin elasticity

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Chung Shan Medical University

Other

Registry information

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Dec 18, 2015
Registry last updated
Dec 18, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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