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Completed

NCT Number: NCT03841214

Study on Prediction of Left Ventricular Remodeling Using ST2

Patients who underwent percutaneous coronary intervention after diagnosis of acute coronary syndrome should be enrolled in the study and follow - up.

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Key information

Conditions

Acute Coronary Syndrome Cardiovascular Diseases Heart Diseases Myocardial Ischemia Vascular Diseases

Age range

19 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Keimyung University Dongsan Hospital

Daegu, Dalseogu, 42601, South Korea

About this study

Obtain written consent for patients who meet all of the selection criteria and who do not meet the exclusion criteria.

ACS(Acute Coronary Syndrome) patients with LV systolic dysfunction(LVEF<50%) on TTE test who underwent successful PCI. At that time, patient proceed with the Baseline blood test(ST2) in hospital.

And then, Medical therapy for 3 months later patient proceed with the Follow-up blood test(ST2) and TTE in OPD.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subjects aged 19 or older
  • Patients with acute coronary syndrome who underwent successful percutaneous coronary intervention
  • Patients with left ventricular ejection fraction less than 50% on transthoracic echocardiography
  • Patients who voluntarily agreed to participate in the study

Exclusion criteria

  • Failure to obtain TIMI 3 flow after procedure
  • If the remaining life span is less than one year
  • Women who are breastfeeding or plan to become pregnant or are planning to become pregnant during the study period

Treatment and study plan

Primary outcomes

  1. ST2 and LV end-diastolic volume index

    Time frame: 3 months

    the correlation between changes of ST2 and LV end-diastolic volume index

Secondary outcomes

  1. ST2 and LV ejection fraction

    Time frame: 3 months

    the correlation between changes of ST2 and LV ejection fraction

  2. ST2 and E over e' ratio

    Time frame: 3 months

    the correlation between changes of ST2 and E over e' ratio

  3. ST2 and LV wall motion score

    Time frame: 3 months

    the correlation between changes of ST2 and LV wall motion score

Sponsors and collaborators

Lead sponsor

Keimyung University Dongsan Medical Center

Other

Registry information

Official study title

Prediction of ST2 for impRovement of Left ventricUlar Systolic funcTion After Percutaneous Coronary Intervention in Patients With acutE Coronary synDrome

Acronym: TRUSTED

Important dates

Study start
2019
Primary completion
2021
Study completion
2021
First posted
Feb 15, 2019
Registry last updated
Mar 31, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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