Study on Dynamic Multimodal Analgesia Regimen Integrated With Traditional Chinese and Western Medicine After Perianal Abscess Surgery

Inclusion criteria

• Aged between 18 and 75 years old (18 ≤ age ≤ 75);
• Diagnosed with primary perianal abscess via digital rectal examination, anorectal ultrasound or MRI, and scheduled for incision and drainage or radical surgery;
• The maximum diameter of the abscess cavity ≥ 2 cm, or with obvious abscess cavity formation;
• Patients are willing and capable of participating in the pain management protocol, fully understand the significance of pain management, and can actively cooperate with study procedures;
• No severe coagulation disorders.

Exclusion criteria

• Complicated with specific infectious diseases such as Crohn's disease and tuberculosis;
• Unclear source of postoperative pain, i.e., the origin of pain cannot be confirmed or the pain is unrelated to surgery;
• Presence of definite contraindications, including drug allergy or inability to tolerate any pain management measures adopted in this trial;
• Pregnant or lactating women;
• Patients unable to cooperate with the study, such as those with cognitive impairment, history of mental illness, communication barriers and other conditions;
• Patients with long-term analgesic medication use and established drug tolerance;
• Complicated with uncontrolled cardiovascular and cerebrovascular diseases (NYHA cardiac function class Ⅲ-Ⅳ), hepatic and renal insufficiency (Child-Pugh class C or eGFR < 30 mL/min/1.73 m²), etc.;
• Abscess secondary to rectal neoplasms, trauma or iatrogenic injury;
• Severe postoperative complications (such as massive hemorrhage, sepsis) or concurrent infections at other sites;
• Patients receiving only non-surgical treatments such as simple needle aspiration of pus.