Skip to main content
OpenTrials
Completed

NCT Number: NCT00303199

Study of ZIO-101 in Multiple Myeloma

The study of safety of a new organic arsenic compound in the treatment of advanced multiple myeloma

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Multiple Myeloma Blood Protein Disorders Cardiovascular Diseases Hematologic Diseases Hemic and Lymphatic Diseases Hemorrhagic Disorders Hemostatic Disorders Immune System Diseases Immunoproliferative Disorders Lymphoproliferative Disorders Neoplasms Neoplasms by Histologic Type Neoplasms, Plasma Cell Paraproteinemias Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

Edmonton, Alberta, Canada

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Subjects with multiple myeloma who have received at least two prior therapies and currently require therapy.

Treatment and study plan

ZIO-101 (Darinaparsin)

Drug

IV zio-101 (Darinaparsin) give for 5 consecutive days to be repeated every 28 days for up to 6 months

Other names: ZIO-101

Primary outcomes

  1. Phase I: toxicity defined in the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events v3.0 (CTCAE) 12/12/03

    Time frame: 6 months

  2. Phase II efficacy using EMBT criteria.

    Time frame: 6 months

  3. Safety

    Time frame: 6 months

Secondary outcomes

  1. Pharmacokinetics of ZIO-101

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Alaunos Therapeutics

Industry

Registry information

Official study title

A Phase I/II Trial of ZIO-101 in Advanced Multiple Myeloma

Important dates

Study start
2006
Primary completion
2007
Study completion
2007
First posted
Mar 15, 2006
Registry last updated
Jul 19, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.