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Completed

NCT Number: NCT00561132

Study of Vanadium Supplement in Patients With Impaired Glucose Tolerance

The purpose of this study was to evaluate if the vanadium can improve the insulin sensitivity in patients with impaired glucose tolerance. Secondary purpose of this study was to assess changes on metabolic profile, weight and blood pressure.

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Key information

Conditions

Prediabetic State Diabetes Mellitus Endocrine System Diseases Glucose Intolerance Glucose Metabolism Disorders Hyperglycemia Hyperinsulinism Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases

Age range

40 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Unidad de Investigacion Medica en Epidemiologia Clinica, Hospital de Especialidades, UMAE, Centro Medico Nacional de Occidente

Guadalajara, Jalisco, 44320, Mexico

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of impaired glucose tolerance
  • Body mass index from 25 to 35 kg/m2
  • History of type 2 diabetes mellitus in the first branch

Exclusion criteria

  • Taking medication with known effects on carbohydrate or insulin metabolism
  • Thyroid diseases
  • Hepatic diseases

Treatment and study plan

Vanadyl sulfate

Dietary Supplement

50 mg twice daily orally for a period of 4 weeks

Other names: Vanadyl sulphate, Vanadyl sulfate hydrate, Vanadyl sulphate hydrate

Magnesium oxide

Other

Validation of similar appearance and weight to the intervention component orally 1 unit (<50 mg) twice daily for a period of 4 weeks

Other names: Calcinated magnesia, Calcined Magnesite, Magnesia

Primary outcomes

  1. Changes on insulin sensitivity assessed with a euglycemic-hyperinsulinemic clamp technique

    Time frame: 4 weeks

Secondary outcomes

  1. Changes on metabolic profile

    Time frame: 4 weeks

  2. Changes on anthropometrical measures

    Time frame: 4 weeks

Sponsors and collaborators

Lead sponsor

Unidad de Investigacion Medica en Epidemiologia Clinica

Other

Collaborators

  • Doctorado en Farmacologia de la Universidad de Guadalajara
  • Fondo para el Fomento a la Investigacion Medica

Registry information

Official study title

Effect of Vanadium on Insulin Sensitivity in Patients With Impaired Glucose Tolerance

Important dates

Study start
2003
Study completion
2004
First posted
Nov 20, 2007
Registry last updated
Nov 20, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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