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NCT Number: NCT06987461

Study of the Use of Non-invasive Ventilation in Bronchial Dilatation Disease

This is a medical record data collection study. The goal of this non-interventional and retrospective study is to describe the characteristics of the population currently being monitored for bronchial dilatation who have been treated with long-term NIV. This is a study based on data from medical records.

The assessment criteria will be :

* Epidemiological characteristics of the population with bronchial dilatation on long-term NIV * Reasons for initiation of NIV * NIV adjustment methods

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Centre Hospitalier Intercommunal de Créteil, Créteil, France

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About this study

Non-invasive ventilation is a treatment sometimes used for severe severe bronchial dilatation, but to date there are no studies its efficacy.

The expected results in this context are :

  • a description of the characteristics of patients with severe bronchial on non-invasive ventilation (NIV)
  • a better understanding, during NIV management, of the settings used, the tolerance and effectiveness of NIV in reducing exacerbations, hospital admissions and patient mortality.
  • move towards better patient management

Data will be extracted from patient medical records and the PMSI.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients over 18 years
  • Predominant diagnosis of bronchiectatic disease, excluding cystic fibrosis, confirmed by computed tomography
  • Introduction of long-term NIV at a given point in the patient's care

Exclusion criteria

  • Patient's opposition to participating in this study
  • Cystic fibrosis
  • Predominant diagnosis of COPD or asthma, traction bronchiectasis, bronchiectasis resulting from focal endobronchial lesion, sarcoidosis or active allergic bronchopulmonary aspergillosis.

Treatment and study plan

Primary outcomes

  1. epidemiological characteristics of the population with bronchial dilation under long-term NIV

    Time frame: Through study completion, an average of 1 year

  2. Reasons for placing under NIV

    Time frame: Through study completion, an average of 1 year

  3. Non-invasive ventilation adjustment modalities

    Time frame: Through study completion, an average of 1 year

Secondary outcomes

  1. Number of acute exacerbations (according to international recommendations) after initiation of NIV

    Time frame: Through study completion, an average of 1 year

  2. Stabilization of respiratory functional tests evolution of FEV1 (%, slope) of PaCO2

    Time frame: Through study completion, an average of 1 year

Study contacts

Contact information is provided by the study sponsor or research team.

Suela DEMIRI, Doctor, Hospital Practitioner

CONTACT

[email protected]

01 57 02 29 63

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Intercommunal Creteil

Other

Registry information

Official study title

Study of the Use of Non-invasive Ventilation in Bronchial Dilatation Disease (BRONCHINIV)

Acronym: BRONCHINIV

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 23, 2025
Registry last updated
May 23, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.