NCT Number: NCT06987461
Study of the Use of Non-invasive Ventilation in Bronchial Dilatation Disease
This is a medical record data collection study. The goal of this non-interventional and retrospective study is to describe the characteristics of the population currently being monitored for bronchial dilatation who have been treated with long-term NIV. This is a study based on data from medical records.
The assessment criteria will be :
* Epidemiological characteristics of the population with bronchial dilatation on long-term NIV * Reasons for initiation of NIV * NIV adjustment methods
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Observational
Primary location
Centre Hospitalier Intercommunal de Créteil, Créteil, France
About this study
Non-invasive ventilation is a treatment sometimes used for severe severe bronchial dilatation, but to date there are no studies its efficacy.
The expected results in this context are :
- a description of the characteristics of patients with severe bronchial on non-invasive ventilation (NIV)
- a better understanding, during NIV management, of the settings used, the tolerance and effectiveness of NIV in reducing exacerbations, hospital admissions and patient mortality.
- move towards better patient management
Data will be extracted from patient medical records and the PMSI.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Patients over 18 years
- Predominant diagnosis of bronchiectatic disease, excluding cystic fibrosis, confirmed by computed tomography
- Introduction of long-term NIV at a given point in the patient's care
Exclusion criteria
- Patient's opposition to participating in this study
- Cystic fibrosis
- Predominant diagnosis of COPD or asthma, traction bronchiectasis, bronchiectasis resulting from focal endobronchial lesion, sarcoidosis or active allergic bronchopulmonary aspergillosis.
Treatment and study plan
Primary outcomes
-
epidemiological characteristics of the population with bronchial dilation under long-term NIV
Time frame: Through study completion, an average of 1 year
-
Reasons for placing under NIV
Time frame: Through study completion, an average of 1 year
-
Non-invasive ventilation adjustment modalities
Time frame: Through study completion, an average of 1 year
Secondary outcomes
-
Number of acute exacerbations (according to international recommendations) after initiation of NIV
Time frame: Through study completion, an average of 1 year
-
Stabilization of respiratory functional tests evolution of FEV1 (%, slope) of PaCO2
Time frame: Through study completion, an average of 1 year
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
Centre Hospitalier Intercommunal Creteil
Other
Registry information
Official study title
Study of the Use of Non-invasive Ventilation in Bronchial Dilatation Disease (BRONCHINIV)
Acronym: BRONCHINIV
Important dates
- Study start
- 2025
- Primary completion
- 2025
- Study completion
- 2025
- First posted
- May 23, 2025
- Registry last updated
- May 23, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.