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Completed

NCT Number: NCT00447200

Study of the Natural Variation in Strokevolume

We would like to investigate the natural variation in the strokevolume of the heart. At the same time we would like to find out the minimal number of heart cycles necessary to discover a 10% increase in strokevolume, after a fluid bolus of 200ml Voluven, when using Esophageal Doppler.

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Key information

Conditions

Stroke Volume Variation

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Rigshospitalet

Copenhagen, Region Sjælland, 2200, Denmark

About this study

We would like to investigate the natural variation in the strokevolume(SV) of the heart. At the same time we would like to find out the minimal number of heart cycles necessary to discover a 10% increase in SV, after a fluid bolus of 200ml Voluven, when using Esophageal Doppler.

Also we will compare the variation in SV both before and after the patients have been fluid optimized, using an algorithm of 10% increase in SV in order to receive another fluid bolus. The equipment used, will be the CardioQ from Deltex medical.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Planned abdominal surgery

Exclusion criteria

  • Oesophageal pathology,
  • Age >90 yr or <18 yr,
  • Alcohol abuse,
  • Aneurism in thoracic aorta

Treatment and study plan

Esophagus Doppler monitoring

Procedure

Fluid optimization

Procedure

Primary outcomes

  1. Strokevolume variation before fluid optimization

  2. Strokevolume variation after fluid optimization

  3. Number of cycles needed in order to detect a 10% strokevolume increase after fluid bolus of 200ml Voluven.

Sponsors and collaborators

Lead sponsor

Rigshospitalet, Denmark

Other

Registry information

Official study title

Study of the Natural Variation in Strokevolume, and Investigation in the Number of Cycles Necessary to Find a 10% Strokevolume Variation Using Esophageal Doppler

Important dates

Study start
2007
Study completion
2007
First posted
Mar 14, 2007
Registry last updated
Oct 15, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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