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NCT Number: NCT06357923

Study of the Evolution of the Expression of the LAMP-2 Protein During the Advance in Age

Recruitment on the RAV pole in consultation or day hospital. Competitive recruitment of subjects > 60 years of age respecting a male/female ratio = 1.

Recruiting

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Key information

Conditions

Aging

Age range

60 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Recruitment on the RAV pole in consultation or day hospital. Competitive recruitment of subjects > 60 years of age respecting a male/female ratio = 1. After explanations and collection consent, collection of the patient's socio-demographic and medical characteristics and then carrying out a Peripheral venous blood sample (2 x 5ml tubes).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Men and women over 60 years of age.

Exclusion criteria

  • Inability to Understand Consent,
  • Non-Security Beneficiaries
  • social, subjects protected by law, subjects deprived of liberty,
  • history of breast cancer,
  • brain tumor,
  • melanoma,
  • colon cancer,
  • lung cancer,
  • prostate cancer,
  • lymphoma,
  • myeloma,
  • syndrome myelodysplastic/myeloproliferative,
  • leukemia,
  • history of radiation therapy.

Treatment and study plan

dosage

Diagnostic Test

Presence of mutation on the gene panel and Frequency of allele variation

Primary outcomes

  1. Expression level of LAMP2 (protein and isoform A and B mRNA)

    Time frame: day 0

    dosage

Secondary outcomes

  1. Presence of mutation in the "Oncomin Myeloid Reasearch Assay" gene panel targeting approximately 40 Different genes

    Time frame: day 0

    dosage

Study contacts

Contact information is provided by the study sponsor or research team.

Andrea CICCONE

CONTACT

[email protected]

0492034702

marion causeret

CONTACT

[email protected]

0492034702

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nice

Other

Registry information

Official study title

Study of the Evolution of the Expression of the LAMP-2 Protein During the Advance as Well as Variations and Allelic Mutations in the Main Genes Involved in the Occurrence of Age-related Myelodysplastic Syndromes

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Apr 10, 2024
Registry last updated
Sep 27, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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